Cargando…

Ovarian function and reproductive outcome after ovarian tissue transplantation: a systematic review

The aim of this systematic review study is to summarize the current knowledge of ovarian tissue transplantation and provide insight on ovarian function, fertility and reproductive outcome following ovarian tissue transplantation. Relevant studies were identified by searching through PubMed, Cochrane...

Descripción completa

Detalles Bibliográficos
Autores principales: Sheshpari, Sepideh, Shahnazi, Mahnaz, Mobarak, Halimeh, Ahmadian, Shahin, Bedate, Alberto Miranda, Nariman-Saleh-Fam, Ziba, Nouri, Mohammad, Rahbarghazi, Reza, Mahdipour, Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883646/
https://www.ncbi.nlm.nih.gov/pubmed/31783875
http://dx.doi.org/10.1186/s12967-019-02149-2
_version_ 1783474421320646656
author Sheshpari, Sepideh
Shahnazi, Mahnaz
Mobarak, Halimeh
Ahmadian, Shahin
Bedate, Alberto Miranda
Nariman-Saleh-Fam, Ziba
Nouri, Mohammad
Rahbarghazi, Reza
Mahdipour, Mahdi
author_facet Sheshpari, Sepideh
Shahnazi, Mahnaz
Mobarak, Halimeh
Ahmadian, Shahin
Bedate, Alberto Miranda
Nariman-Saleh-Fam, Ziba
Nouri, Mohammad
Rahbarghazi, Reza
Mahdipour, Mahdi
author_sort Sheshpari, Sepideh
collection PubMed
description The aim of this systematic review study is to summarize the current knowledge of ovarian tissue transplantation and provide insight on ovarian function, fertility and reproductive outcome following ovarian tissue transplantation. Relevant studies were identified by searching through PubMed, Cochrane Library, Embase, ProQuest, and Scopus databases until August 2018. Ovarian function by examination of the hormonal level was evaluated, together with follicular growth, the return of menstrual cycle and assessment of reproductive consequences: pregnancy, miscarriage rates and live birth after transplantation. Studies including female patients aged between 22 and 49 years that were subjected to ovarian tissue transplantation were considered. A total of 1185 studies were identified in the primary search. Titles and abstracts were screened for assessment of the inclusion criteria. Finally, twenty-five articles met the criteria and were included in this study. In general, 70% of patients that underwent ovarian tissue transplantation had ovarian and endocrine function restoration as well as follicular growth. Pregnancy was reported with 52% of the patients. The available evidence suggests that ovarian tissue transplantation is a useful and an applied approach to restore hormonal function, endocrine balance and eventually fertility outcomes in patients that are predisposed to lose their fertility, diagnosed with premature ovarian failure (POF), as well as women undergoing cancer treatments. Identification of the techniques with the lowest invasions for follicular and oocyte development after ovarian tissue transplantation aiming to reduce probable adverse effects after treatment is indispensable.
format Online
Article
Text
id pubmed-6883646
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-68836462019-12-03 Ovarian function and reproductive outcome after ovarian tissue transplantation: a systematic review Sheshpari, Sepideh Shahnazi, Mahnaz Mobarak, Halimeh Ahmadian, Shahin Bedate, Alberto Miranda Nariman-Saleh-Fam, Ziba Nouri, Mohammad Rahbarghazi, Reza Mahdipour, Mahdi J Transl Med Review The aim of this systematic review study is to summarize the current knowledge of ovarian tissue transplantation and provide insight on ovarian function, fertility and reproductive outcome following ovarian tissue transplantation. Relevant studies were identified by searching through PubMed, Cochrane Library, Embase, ProQuest, and Scopus databases until August 2018. Ovarian function by examination of the hormonal level was evaluated, together with follicular growth, the return of menstrual cycle and assessment of reproductive consequences: pregnancy, miscarriage rates and live birth after transplantation. Studies including female patients aged between 22 and 49 years that were subjected to ovarian tissue transplantation were considered. A total of 1185 studies were identified in the primary search. Titles and abstracts were screened for assessment of the inclusion criteria. Finally, twenty-five articles met the criteria and were included in this study. In general, 70% of patients that underwent ovarian tissue transplantation had ovarian and endocrine function restoration as well as follicular growth. Pregnancy was reported with 52% of the patients. The available evidence suggests that ovarian tissue transplantation is a useful and an applied approach to restore hormonal function, endocrine balance and eventually fertility outcomes in patients that are predisposed to lose their fertility, diagnosed with premature ovarian failure (POF), as well as women undergoing cancer treatments. Identification of the techniques with the lowest invasions for follicular and oocyte development after ovarian tissue transplantation aiming to reduce probable adverse effects after treatment is indispensable. BioMed Central 2019-11-29 /pmc/articles/PMC6883646/ /pubmed/31783875 http://dx.doi.org/10.1186/s12967-019-02149-2 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Sheshpari, Sepideh
Shahnazi, Mahnaz
Mobarak, Halimeh
Ahmadian, Shahin
Bedate, Alberto Miranda
Nariman-Saleh-Fam, Ziba
Nouri, Mohammad
Rahbarghazi, Reza
Mahdipour, Mahdi
Ovarian function and reproductive outcome after ovarian tissue transplantation: a systematic review
title Ovarian function and reproductive outcome after ovarian tissue transplantation: a systematic review
title_full Ovarian function and reproductive outcome after ovarian tissue transplantation: a systematic review
title_fullStr Ovarian function and reproductive outcome after ovarian tissue transplantation: a systematic review
title_full_unstemmed Ovarian function and reproductive outcome after ovarian tissue transplantation: a systematic review
title_short Ovarian function and reproductive outcome after ovarian tissue transplantation: a systematic review
title_sort ovarian function and reproductive outcome after ovarian tissue transplantation: a systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883646/
https://www.ncbi.nlm.nih.gov/pubmed/31783875
http://dx.doi.org/10.1186/s12967-019-02149-2
work_keys_str_mv AT sheshparisepideh ovarianfunctionandreproductiveoutcomeafterovariantissuetransplantationasystematicreview
AT shahnazimahnaz ovarianfunctionandreproductiveoutcomeafterovariantissuetransplantationasystematicreview
AT mobarakhalimeh ovarianfunctionandreproductiveoutcomeafterovariantissuetransplantationasystematicreview
AT ahmadianshahin ovarianfunctionandreproductiveoutcomeafterovariantissuetransplantationasystematicreview
AT bedatealbertomiranda ovarianfunctionandreproductiveoutcomeafterovariantissuetransplantationasystematicreview
AT narimansalehfamziba ovarianfunctionandreproductiveoutcomeafterovariantissuetransplantationasystematicreview
AT nourimohammad ovarianfunctionandreproductiveoutcomeafterovariantissuetransplantationasystematicreview
AT rahbarghazireza ovarianfunctionandreproductiveoutcomeafterovariantissuetransplantationasystematicreview
AT mahdipourmahdi ovarianfunctionandreproductiveoutcomeafterovariantissuetransplantationasystematicreview