ReorientExpress: reference-free orientation of nanopore cDNA reads with deep learning

We describe ReorientExpress, a method to perform reference-free orientation of transcriptomic long sequencing reads. ReorientExpress uses deep learning to correctly predict the orientation of the majority of reads, and in particular when trained on a closely related species or in combination with re...

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Detalles Bibliográficos
Autores principales: Ruiz-Reche, Angel, Srivastava, Akanksha, Indi, Joel A., de la Rubia, Ivan, Eyras, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883653/
https://www.ncbi.nlm.nih.gov/pubmed/31783882
http://dx.doi.org/10.1186/s13059-019-1884-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883653/
https://www.ncbi.nlm.nih.gov/pubmed/31783882
http://dx.doi.org/10.1186/s13059-019-1884-z

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