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ReorientExpress: reference-free orientation of nanopore cDNA reads with deep learning
We describe ReorientExpress, a method to perform reference-free orientation of transcriptomic long sequencing reads. ReorientExpress uses deep learning to correctly predict the orientation of the majority of reads, and in particular when trained on a closely related species or in combination with re...
Autores principales: | Ruiz-Reche, Angel, Srivastava, Akanksha, Indi, Joel A., de la Rubia, Ivan, Eyras, Eduardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883653/ https://www.ncbi.nlm.nih.gov/pubmed/31783882 http://dx.doi.org/10.1186/s13059-019-1884-z |
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