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Orotracheal treprostinil administration attenuates bleomycin-induced lung injury, vascular remodeling, and fibrosis in mice
Pulmonary fibrosis is a progressive disease characterized by disruption of lung architecture and deregulation of the pulmonary function. Prostacyclin, a metabolite of arachidonic acid, is a potential disease mediator since it exerts anti-inflammatory and anti-fibrotic actions. We investigated the ef...
Autores principales: | Nikitopoulou, Ioanna, Manitsopoulos, Nikolaos, Kotanidou, Anastasia, Tian, Xia, Petrovic, Aleksandar, Magkou, Christina, Ninou, Ioanna, Aidinis, Vassilis, Schermuly, Ralph T., Kosanovic, Djuro, Orfanos, Stylianos E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883672/ https://www.ncbi.nlm.nih.gov/pubmed/31819797 http://dx.doi.org/10.1177/2045894019881954 |
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