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Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment
BACKGROUND: Cisplatin plus pemetrexed combination therapy is considered the standard treatment for patients with advanced, non-squamous, non-small-cell lung cancer (NSCLC). However, advanced NSCLC has a 5-year survival rate of below 10%, which is mainly due to therapy resistance. We previously showe...
Autores principales: | Gao, Yanyun, Dorn, Patrick, Liu, Shengchen, Deng, Haibin, Hall, Sean R. R., Peng, Ren-Wang, Schmid, Ralph A., Marti, Thomas M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883680/ https://www.ncbi.nlm.nih.gov/pubmed/31798346 http://dx.doi.org/10.1186/s12935-019-1037-1 |
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