Cargando…

Monocarboxylate transporter 1 promotes classical microglial activation and pro-inflammatory effect via 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3

BACKGROUND: Microglia, the resident macrophages of central nervous system, have been initially categorized into two opposite phenotypes: classical activation related to pro-inflammatory responses and alternative activation corresponding with anti-inflammatory reactions and tissue remodeling. The cor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kong, Liang, Wang, Zehua, Liang, Xiaohong, Wang, Yue, Gao, Lifen, Ma, Chunhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883695/ https://www.ncbi.nlm.nih.gov/pubmed/31779643 http://dx.doi.org/10.1186/s12974-019-1648-4

Ejemplares similares

6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 and 4: A pair of valves for fine-tuning of glucose metabolism in human cancer
por: Yi, Mei, et al.
Publicado: (2018)

Amylin deposition activates HIF1α and 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 (PFKFB3) signaling in failing hearts of non-human primates
por: Liu, Miao, et al.
Publicado: (2021)

Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells
por: Carlet, Michela, et al.
Publicado: (2010)

International practices in the dietary management of fructose 1-6 biphosphatase deficiency
por: Pinto, A., et al.
Publicado: (2018)

KLF9 (Kruppel Like Factor 9) induced PFKFB3 (6-Phosphofructo-2-Kinase/Fructose-2, 6-Biphosphatase 3) downregulation inhibits the proliferation, metastasis and aerobic glycolysis of cutaneous squamous cell carcinoma cells
por: Xing, Jiahua, et al.
Publicado: (2021)

The role of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 in esophageal squamous cell carcinoma
por: Bao, Junhui, et al.
Publicado: (2020)

Long intergenic non-protein coding RNA 115 (LINC00115) aggravates retinoblastoma progression by targeting microRNA miR-489-3p that downregulates 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2)
por: Ji, Fang, et al.
Publicado: (2022)

Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase Modulates Oscillations of Pancreatic Islet Metabolism
por: Merrins, Matthew J., et al.
Publicado: (2012)

Balancing glycolytic flux: the role of 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatases in cancer metabolism
por: Ros, Susana, et al.
Publicado: (2013)

Fructose-2,6-Bisphosphate synthesis by 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth
por: Chesney, Jason, et al.
Publicado: (2014)

Liver X Receptor α Is Involved in the Transcriptional Regulation of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase Gene
por: Zhao, Li-Feng, et al.
Publicado: (2012)

Increased expression and phosphorylation of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoforms in urinary exosomes in pre-eclampsia
por: Ellis, R., et al.
Publicado: (2019)

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 spatially mediates autophagy through the AMPK signaling pathway
por: Yan, Siyuan, et al.
Publicado: (2017)

Expression of Alternative Splice Variants of 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase-4 in Normoxic and Hypoxic Melanoma Cells
por: Trojan, Sonia E., et al.
Publicado: (2021)

Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis
por: Tillie, Renée J. H. A., et al.
Publicado: (2021)

Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB4) as a Novel Autophagy Regulator by High Content shRNA Screening
por: Strohecker, Anne M., et al.
Publicado: (2015)

Glucagon induces translocation of glucokinase from the cytoplasm to the nucleus of hepatocytes by transfer between 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase-2 and the glucokinase regulatory protein
por: Cullen, Kirsty S., et al.
Publicado: (2014)

Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation
por: Telang, Sucheta, et al.
Publicado: (2012)

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase Suppresses Neuronal Apoptosis by Increasing Glycolysis and “cyclin-dependent kinase 1-Mediated Phosphorylation of p27 After Traumatic Spinal Cord Injury in Rats
por: Gao, Liansheng, et al.
Publicado: (2020)

Evolution of Allosteric Citrate Binding Sites on 6-phosphofructo-1-kinase
por: Usenik, Aleksandra, et al.
Publicado: (2010)

Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism
por: Klarer, Alden C, et al.
Publicado: (2014)

Succinate Dehydrogenase‐Deficient Renal Cancer Featuring Fructose‐1,6‐Biphosphatase Loss, Pyruvate Kinase M2 Overexpression, and SWI/SNF Chromatin Remodeling Complex Aberrations: A Rare Case Report
por: Szymanski, Michal, et al.
Publicado: (2021)

Posttranslational Modification of 6-phosphofructo-1-kinase as an Important Feature of Cancer Metabolism
por: Šmerc, Andreja, et al.
Publicado: (2011)

Simultaneous inhibition of the estrogen receptor and 6-phosphofructo-2-kinase (PFKFB3) for the treatment of ER+ breast cancer
por: Imbert-Fernandez, Yoannis, et al.
Publicado: (2014)

Targeting the sugar metabolism of tumors with a first-in-class 6-phosphofructo-2-kinase (PFKFB4) inhibitor
por: Chesney, Jason, et al.
Publicado: (2015)

Overexpression of a modified 6-phosphofructo-1-kinase results in an increased itaconic acid productivity in Aspergillus niger
por: van der Straat, Laura, et al.
Publicado: (2013)

Effect of the cancer specific shorter form of human 6-phosphofructo-1-kinase on the metabolism of the yeast Saccharomyces cerevisiae
por: Andrejc, Darjan, et al.
Publicado: (2017)

Dry-milled flour rice ‘Seolgaeng’ harbors a mutated fructose-6-phosphate 2-kinase/fructose-2,6-bisphosphatase2
por: Kang, Ju-Won, et al.
Publicado: (2023)

6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27
por: Yalcin, A, et al.
Publicado: (2014)

Fructose 2,6-Bisphosphate in Cancer Cell Metabolism
por: Bartrons, Ramon, et al.
Publicado: (2018)

Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6
por: Ding, Lu, et al.
Publicado: (2023)

Transcription factor Zhx2 restricts NK cell maturation and suppresses their antitumor immunity
por: Tan, Siyu, et al.
Publicado: (2021)

Fructose-2,6-bisphosphate links glucose to survival and growth
por: Yalcin, Abdullah, et al.
Publicado: (2014)

Cooperative transport mechanism of human monocarboxylate transporter 2
por: Zhang, Bo, et al.
Publicado: (2020)

Monocarboxylate transporters in cancer
por: Payen, Valéry L., et al.
Publicado: (2019)

Monocarboxylate Transporters: Role and Regulation in Corneal Diabetes
por: Shrestha, Pawan, et al.
Publicado: (2022)

One-pot formation of 2,4-di- or 2,4,6-tri-olefinic monocarboxylic acids by straight chain C4-extension
por: Sobotta, Jessica, et al.
Publicado: (2017)

Fructose-1,6-Bisphosphatase 2 Inhibits Oral Squamous Cell Carcinoma Tumorigenesis and Glucose Metabolism via Downregulation of c-Myc
por: Wang, Liang, et al.
Publicado: (2022)

Monocarboxylate transporters in the brain and in cancer()
por: Pérez-Escuredo, Jhudit, et al.
Publicado: (2016)

PET Imaging of Fructose Metabolism in a Rodent Model of Neuroinflammation with 6-[(18)F]fluoro-6-deoxy-D-fructose
por: Boyle, Amanda J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jp1vrr7gggehjog2riu4fqlbs1