A Novel Mouse Model of MYO7A USH1B Reveals Auditory and Visual System Haploinsufficiencies

Usher’s syndrome is the most common combined blindness–deafness disorder with USH1B, caused by mutations in MYO7A, resulting in the most severe phenotype. The existence of numerous, naturally occurring shaker1 mice harboring variable MYO7A mutations on different genetic backgrounds has complicated t...

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Detalles Bibliográficos
Autores principales: Calabro, Kaitlyn R., Boye, Sanford L., Choudhury, Shreyasi, Fajardo, Diego, Peterson, James J., Li, Wei, Crosson, Sean M., Kim, Mi-Jung, Ding, Dalian, Salvi, Richard, Someya, Shinichi, Boye, Shannon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883748/
https://www.ncbi.nlm.nih.gov/pubmed/31824252
http://dx.doi.org/10.3389/fnins.2019.01255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883748/
https://www.ncbi.nlm.nih.gov/pubmed/31824252
http://dx.doi.org/10.3389/fnins.2019.01255

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