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The relationship between stress during pregnancy with leptin and cortisol blood concentrations and complications of pregnancy in the mother

OBJECTIVE: Pregnancy is one of the most stressful periods a woman experiences in her life. The present study was an attempt to determine the relationship between maternal stress during pregnancy and cortisol plus maternal serum leptin concentrations as well as pregnancy outcomes. MATERIAL AND METHOD...

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Autores principales: Rabiepour, Soheila, Saboory, Ehsan, Abedi, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883754/
https://www.ncbi.nlm.nih.gov/pubmed/31298513
http://dx.doi.org/10.4274/jtgga.galenos.2019.2019.0010
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author Rabiepour, Soheila
Saboory, Ehsan
Abedi, Maryam
author_facet Rabiepour, Soheila
Saboory, Ehsan
Abedi, Maryam
author_sort Rabiepour, Soheila
collection PubMed
description OBJECTIVE: Pregnancy is one of the most stressful periods a woman experiences in her life. The present study was an attempt to determine the relationship between maternal stress during pregnancy and cortisol plus maternal serum leptin concentrations as well as pregnancy outcomes. MATERIAL AND METHODS: This longitudinal study was conducted on 90 pregnant women in Miandoab city between 2015 and 2016. The samples were chosen from mothers with a gestational age of 24 to 28 weeks. The participants were asked to complete Cohen’s Perceived Stress Scale (PSS) and a demographic questionnaire and blood samples were taken from them. The mothers were then tracked with four-week intervals until the time of delivery and were asked to complete Cohen’s PSS each time along with a questionnaire related to maternal outcomes. Again, a blood sample was taken at the time of delivery. Data analysis was performed using SPSS 16. Descriptive statistics, Pearson’s correlation coefficient, and the t-test were employed for analysis. RESULTS: A significant relationship was found between maternal stress and preeclampsia (p=0.008). The relationships between preterm childbirth and maternal cortisol concentrations in weeks 24-28 (p=0.015), and between preterm childbirth and maternal leptin concentrations at the time of delivery (p=0.007) were also found to be significant. CONCLUSION: Pregnancy and labor, as physically and mentally stressful events, can affect women’s physiologic and psychological indicators. As a consequence, during pregnancy, the cortisol and leptin index changes in response to the activity of the hypothalamic-pituitary axis and autonomic nervous system under stress.
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spelling pubmed-68837542019-12-09 The relationship between stress during pregnancy with leptin and cortisol blood concentrations and complications of pregnancy in the mother Rabiepour, Soheila Saboory, Ehsan Abedi, Maryam J Turk Ger Gynecol Assoc Original Investigation OBJECTIVE: Pregnancy is one of the most stressful periods a woman experiences in her life. The present study was an attempt to determine the relationship between maternal stress during pregnancy and cortisol plus maternal serum leptin concentrations as well as pregnancy outcomes. MATERIAL AND METHODS: This longitudinal study was conducted on 90 pregnant women in Miandoab city between 2015 and 2016. The samples were chosen from mothers with a gestational age of 24 to 28 weeks. The participants were asked to complete Cohen’s Perceived Stress Scale (PSS) and a demographic questionnaire and blood samples were taken from them. The mothers were then tracked with four-week intervals until the time of delivery and were asked to complete Cohen’s PSS each time along with a questionnaire related to maternal outcomes. Again, a blood sample was taken at the time of delivery. Data analysis was performed using SPSS 16. Descriptive statistics, Pearson’s correlation coefficient, and the t-test were employed for analysis. RESULTS: A significant relationship was found between maternal stress and preeclampsia (p=0.008). The relationships between preterm childbirth and maternal cortisol concentrations in weeks 24-28 (p=0.015), and between preterm childbirth and maternal leptin concentrations at the time of delivery (p=0.007) were also found to be significant. CONCLUSION: Pregnancy and labor, as physically and mentally stressful events, can affect women’s physiologic and psychological indicators. As a consequence, during pregnancy, the cortisol and leptin index changes in response to the activity of the hypothalamic-pituitary axis and autonomic nervous system under stress. Galenos Publishing 2019-12 2019-11-28 /pmc/articles/PMC6883754/ /pubmed/31298513 http://dx.doi.org/10.4274/jtgga.galenos.2019.2019.0010 Text en © Copyright 2019 by the Turkish-German Gynecological Education and Research Foundation http://creativecommons.org/licenses/by/2.5/ Journal of the Turkish-German Gynecological Association published by Galenos Publishing House.
spellingShingle Original Investigation
Rabiepour, Soheila
Saboory, Ehsan
Abedi, Maryam
The relationship between stress during pregnancy with leptin and cortisol blood concentrations and complications of pregnancy in the mother
title The relationship between stress during pregnancy with leptin and cortisol blood concentrations and complications of pregnancy in the mother
title_full The relationship between stress during pregnancy with leptin and cortisol blood concentrations and complications of pregnancy in the mother
title_fullStr The relationship between stress during pregnancy with leptin and cortisol blood concentrations and complications of pregnancy in the mother
title_full_unstemmed The relationship between stress during pregnancy with leptin and cortisol blood concentrations and complications of pregnancy in the mother
title_short The relationship between stress during pregnancy with leptin and cortisol blood concentrations and complications of pregnancy in the mother
title_sort relationship between stress during pregnancy with leptin and cortisol blood concentrations and complications of pregnancy in the mother
topic Original Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883754/
https://www.ncbi.nlm.nih.gov/pubmed/31298513
http://dx.doi.org/10.4274/jtgga.galenos.2019.2019.0010
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