Long-term in vivo microscopy of CAR T cell dynamics during eradication of CNS lymphoma in mice

T cells expressing anti-CD19 chimeric antigen receptors (CARs) demonstrate impressive efficacy in the treatment of systemic B cell malignancies, including B cell lymphoma. However, their effect on primary central nervous system lymphoma (PCNSL) is unknown. Additionally, the detailed cellular dynamic...

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Detalles Bibliográficos
Autores principales: Mulazzani, Matthias, Fräßle, Simon P., von Mücke-Heim, Iven, Langer, Sigrid, Zhou, Xiaolan, Ishikawa-Ankerhold, Hellen, Leube, Justin, Zhang, Wenlong, Dötsch, Sarah, Svec, Mortimer, Rudelius, Martina, Dreyling, Martin, von Bergwelt-Baildon, Michael, Straube, Andreas, Buchholz, Veit R., Busch, Dirk H., von Baumgarten, Louisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883823/
https://www.ncbi.nlm.nih.gov/pubmed/31712432
http://dx.doi.org/10.1073/pnas.1903854116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883823/
https://www.ncbi.nlm.nih.gov/pubmed/31712432
http://dx.doi.org/10.1073/pnas.1903854116

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