Cargando…

A Rare Case of Acute Kidney Injury Due to Levofloxacin-induced Crystal Nephropathy

Crystal-induced acute kidney injury (AKI) is caused by the intratubular precipitation of crystals, which results in obstruction and kidney injury. Levofloxacin is commonly used fluoroquinolone antibiotic especially for respiratory and urinary tract infections. It rarely causes any serious adverse ev...

Descripción completa

Detalles Bibliográficos
Autores principales: Ansari, Faizan Ahmed, Manuel, Sonu, Dwivedi, Rohan, Boraiah, Shashikiran Kabbare, Raju, Sree Bhushan, Uppin, Megha, Sharma, Alok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883864/
https://www.ncbi.nlm.nih.gov/pubmed/31798226
http://dx.doi.org/10.4103/ijn.IJN_295_18
Descripción
Sumario:Crystal-induced acute kidney injury (AKI) is caused by the intratubular precipitation of crystals, which results in obstruction and kidney injury. Levofloxacin is commonly used fluoroquinolone antibiotic especially for respiratory and urinary tract infections. It rarely causes any serious adverse events. Several cases of crystal nephropathy after ciprofloxacin use have been reported. Pre-existing renal dysfunction, high dose of the drug, and advanced age are considered as risk factors. To best of our knowledge, only two cases of crystal nephropathy due to levofloxacin use have been reported, we add a new one to it. The patient responded to conservative treatment with complete recovery on follow-up.