A Rare Case of Acute Kidney Injury Due to Levofloxacin-induced Crystal Nephropathy

Crystal-induced acute kidney injury (AKI) is caused by the intratubular precipitation of crystals, which results in obstruction and kidney injury. Levofloxacin is commonly used fluoroquinolone antibiotic especially for respiratory and urinary tract infections. It rarely causes any serious adverse ev...

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Autores principales: Ansari, Faizan Ahmed, Manuel, Sonu, Dwivedi, Rohan, Boraiah, Shashikiran Kabbare, Raju, Sree Bhushan, Uppin, Megha, Sharma, Alok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883864/
https://www.ncbi.nlm.nih.gov/pubmed/31798226
http://dx.doi.org/10.4103/ijn.IJN_295_18
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author Ansari, Faizan Ahmed
Manuel, Sonu
Dwivedi, Rohan
Boraiah, Shashikiran Kabbare
Raju, Sree Bhushan
Uppin, Megha
Sharma, Alok
author_facet Ansari, Faizan Ahmed
Manuel, Sonu
Dwivedi, Rohan
Boraiah, Shashikiran Kabbare
Raju, Sree Bhushan
Uppin, Megha
Sharma, Alok
author_sort Ansari, Faizan Ahmed
collection PubMed
description Crystal-induced acute kidney injury (AKI) is caused by the intratubular precipitation of crystals, which results in obstruction and kidney injury. Levofloxacin is commonly used fluoroquinolone antibiotic especially for respiratory and urinary tract infections. It rarely causes any serious adverse events. Several cases of crystal nephropathy after ciprofloxacin use have been reported. Pre-existing renal dysfunction, high dose of the drug, and advanced age are considered as risk factors. To best of our knowledge, only two cases of crystal nephropathy due to levofloxacin use have been reported, we add a new one to it. The patient responded to conservative treatment with complete recovery on follow-up.
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spelling pubmed-68838642019-12-03 A Rare Case of Acute Kidney Injury Due to Levofloxacin-induced Crystal Nephropathy Ansari, Faizan Ahmed Manuel, Sonu Dwivedi, Rohan Boraiah, Shashikiran Kabbare Raju, Sree Bhushan Uppin, Megha Sharma, Alok Indian J Nephrol Case Report Crystal-induced acute kidney injury (AKI) is caused by the intratubular precipitation of crystals, which results in obstruction and kidney injury. Levofloxacin is commonly used fluoroquinolone antibiotic especially for respiratory and urinary tract infections. It rarely causes any serious adverse events. Several cases of crystal nephropathy after ciprofloxacin use have been reported. Pre-existing renal dysfunction, high dose of the drug, and advanced age are considered as risk factors. To best of our knowledge, only two cases of crystal nephropathy due to levofloxacin use have been reported, we add a new one to it. The patient responded to conservative treatment with complete recovery on follow-up. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6883864/ /pubmed/31798226 http://dx.doi.org/10.4103/ijn.IJN_295_18 Text en Copyright: © 2019 Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Ansari, Faizan Ahmed
Manuel, Sonu
Dwivedi, Rohan
Boraiah, Shashikiran Kabbare
Raju, Sree Bhushan
Uppin, Megha
Sharma, Alok
A Rare Case of Acute Kidney Injury Due to Levofloxacin-induced Crystal Nephropathy
title A Rare Case of Acute Kidney Injury Due to Levofloxacin-induced Crystal Nephropathy
title_full A Rare Case of Acute Kidney Injury Due to Levofloxacin-induced Crystal Nephropathy
title_fullStr A Rare Case of Acute Kidney Injury Due to Levofloxacin-induced Crystal Nephropathy
title_full_unstemmed A Rare Case of Acute Kidney Injury Due to Levofloxacin-induced Crystal Nephropathy
title_short A Rare Case of Acute Kidney Injury Due to Levofloxacin-induced Crystal Nephropathy
title_sort rare case of acute kidney injury due to levofloxacin-induced crystal nephropathy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883864/
https://www.ncbi.nlm.nih.gov/pubmed/31798226
http://dx.doi.org/10.4103/ijn.IJN_295_18
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