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The Effects of Melatonin on the Descending Pain Inhibitory System and Neural Plasticity Markers in Breast Cancer Patients Receiving Chemotherapy: Randomized, Double-Blinded, Placebo-Controlled Trial
Background: Adjuvant chemotherapy for breast cancer (ACBC) has been associated with fatigue, pain, depressive symptoms, and disturbed sleep. And, previous studies in non-cancer patients showed that melatonin could improve the descending pain modulatory system (DPMS). We tested the hypothesis that me...
Autores principales: | Palmer, Ana Claudia Souza, Souza, Andressa, dos Santos, Vinicius Souza, Cavalheiro, José Antônio Crespo, Schuh, Fernando, Zucatto, Angela Erguy, Biazus, Jorge Villanova, Torres, Iraci Lucena Da S., Fregni, Felipe, Caumo, Wolnei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883914/ https://www.ncbi.nlm.nih.gov/pubmed/31824318 http://dx.doi.org/10.3389/fphar.2019.01382 |
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