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Impact Of Penetratin Stereochemistry On The Oral Bioavailability Of Insulin-Loaded Solid Lipid Nanoparticles

PURPOSE: This study evaluated the stereoisomeric effect of L- and D-penetratin—cell-penetrating peptides (CPPs)—incorporated insulin-loaded solid lipid nanoparticles (INS-SLNs) on the bioavailability (BA) of oral insulin (INS). METHODS: Insulin-loaded solid nanoparticles, L-penetratin-INS-SLNs (LP-I...

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Detalles Bibliográficos
Autores principales:	Alsulays, Bader B, Anwer, Md Khalid, Soliman, Gamal A, Alshehri, Sultan M, Khafagy, El-Sayed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883942/ https://www.ncbi.nlm.nih.gov/pubmed/31819423 http://dx.doi.org/10.2147/IJN.S225086

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