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An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer

Cervical cancer is still an important cause of mortality among women in a number of countries. There are effective methods of prevention and early diagnosis, but they require well-trained medical professionals including cytologists. Within this project, we built a prototype of a new device together...

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Autores principales: Lasyk, Łukasz, Barbasz, Jakub, Żuk, Paweł, Prusaczyk, Artur, Włodarczyk, Tomasz, Prokurat, Ewa, Olszewski, Wojciech, Bidziński, Mariusz, Baszuk, Piotr, Gronwald, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883966/
https://www.ncbi.nlm.nih.gov/pubmed/31798334
http://dx.doi.org/10.5114/wo.2019.85617
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author Lasyk, Łukasz
Barbasz, Jakub
Żuk, Paweł
Prusaczyk, Artur
Włodarczyk, Tomasz
Prokurat, Ewa
Olszewski, Wojciech
Bidziński, Mariusz
Baszuk, Piotr
Gronwald, Jacek
author_facet Lasyk, Łukasz
Barbasz, Jakub
Żuk, Paweł
Prusaczyk, Artur
Włodarczyk, Tomasz
Prokurat, Ewa
Olszewski, Wojciech
Bidziński, Mariusz
Baszuk, Piotr
Gronwald, Jacek
author_sort Lasyk, Łukasz
collection PubMed
description Cervical cancer is still an important cause of mortality among women in a number of countries. There are effective methods of prevention and early diagnosis, but they require well-trained medical professionals including cytologists. Within this project, we built a prototype of a new device together with implemented software using U-NET and CNN architectures of neural networks (ANN), to convert the currently used optical microscopes into fully independent scanning and evaluating systems for cytological samples. To evaluate the specificity and sensitivity of the system, 2058 (2000 normal and 58 abnormal samples) consecutive liquid-based cytology (LBC) samples were analysed. The observed sensitivity and specificity to distinguish normal and abnormal samples was 100%. We observed slight incompatibility in the evaluation of the type of abnormality. The use of ANN is promising for increasing the effectiveness of cervical screening. The low cost of neural network usage further increases the potential areas of application of the presented method. Further refinement of neural networks on a larger sample size is required to evaluate the software.
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spelling pubmed-68839662019-12-03 An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer Lasyk, Łukasz Barbasz, Jakub Żuk, Paweł Prusaczyk, Artur Włodarczyk, Tomasz Prokurat, Ewa Olszewski, Wojciech Bidziński, Mariusz Baszuk, Piotr Gronwald, Jacek Contemp Oncol (Pozn) Original Paper Cervical cancer is still an important cause of mortality among women in a number of countries. There are effective methods of prevention and early diagnosis, but they require well-trained medical professionals including cytologists. Within this project, we built a prototype of a new device together with implemented software using U-NET and CNN architectures of neural networks (ANN), to convert the currently used optical microscopes into fully independent scanning and evaluating systems for cytological samples. To evaluate the specificity and sensitivity of the system, 2058 (2000 normal and 58 abnormal samples) consecutive liquid-based cytology (LBC) samples were analysed. The observed sensitivity and specificity to distinguish normal and abnormal samples was 100%. We observed slight incompatibility in the evaluation of the type of abnormality. The use of ANN is promising for increasing the effectiveness of cervical screening. The low cost of neural network usage further increases the potential areas of application of the presented method. Further refinement of neural networks on a larger sample size is required to evaluate the software. Termedia Publishing House 2019-10-31 2019 /pmc/articles/PMC6883966/ /pubmed/31798334 http://dx.doi.org/10.5114/wo.2019.85617 Text en Copyright: © 2019 Termedia Sp. z o. o. http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Lasyk, Łukasz
Barbasz, Jakub
Żuk, Paweł
Prusaczyk, Artur
Włodarczyk, Tomasz
Prokurat, Ewa
Olszewski, Wojciech
Bidziński, Mariusz
Baszuk, Piotr
Gronwald, Jacek
An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer
title An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer
title_full An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer
title_fullStr An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer
title_full_unstemmed An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer
title_short An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer
title_sort evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883966/
https://www.ncbi.nlm.nih.gov/pubmed/31798334
http://dx.doi.org/10.5114/wo.2019.85617
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