Cargando…
An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer
Cervical cancer is still an important cause of mortality among women in a number of countries. There are effective methods of prevention and early diagnosis, but they require well-trained medical professionals including cytologists. Within this project, we built a prototype of a new device together...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883966/ https://www.ncbi.nlm.nih.gov/pubmed/31798334 http://dx.doi.org/10.5114/wo.2019.85617 |
_version_ | 1783474481564483584 |
---|---|
author | Lasyk, Łukasz Barbasz, Jakub Żuk, Paweł Prusaczyk, Artur Włodarczyk, Tomasz Prokurat, Ewa Olszewski, Wojciech Bidziński, Mariusz Baszuk, Piotr Gronwald, Jacek |
author_facet | Lasyk, Łukasz Barbasz, Jakub Żuk, Paweł Prusaczyk, Artur Włodarczyk, Tomasz Prokurat, Ewa Olszewski, Wojciech Bidziński, Mariusz Baszuk, Piotr Gronwald, Jacek |
author_sort | Lasyk, Łukasz |
collection | PubMed |
description | Cervical cancer is still an important cause of mortality among women in a number of countries. There are effective methods of prevention and early diagnosis, but they require well-trained medical professionals including cytologists. Within this project, we built a prototype of a new device together with implemented software using U-NET and CNN architectures of neural networks (ANN), to convert the currently used optical microscopes into fully independent scanning and evaluating systems for cytological samples. To evaluate the specificity and sensitivity of the system, 2058 (2000 normal and 58 abnormal samples) consecutive liquid-based cytology (LBC) samples were analysed. The observed sensitivity and specificity to distinguish normal and abnormal samples was 100%. We observed slight incompatibility in the evaluation of the type of abnormality. The use of ANN is promising for increasing the effectiveness of cervical screening. The low cost of neural network usage further increases the potential areas of application of the presented method. Further refinement of neural networks on a larger sample size is required to evaluate the software. |
format | Online Article Text |
id | pubmed-6883966 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-68839662019-12-03 An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer Lasyk, Łukasz Barbasz, Jakub Żuk, Paweł Prusaczyk, Artur Włodarczyk, Tomasz Prokurat, Ewa Olszewski, Wojciech Bidziński, Mariusz Baszuk, Piotr Gronwald, Jacek Contemp Oncol (Pozn) Original Paper Cervical cancer is still an important cause of mortality among women in a number of countries. There are effective methods of prevention and early diagnosis, but they require well-trained medical professionals including cytologists. Within this project, we built a prototype of a new device together with implemented software using U-NET and CNN architectures of neural networks (ANN), to convert the currently used optical microscopes into fully independent scanning and evaluating systems for cytological samples. To evaluate the specificity and sensitivity of the system, 2058 (2000 normal and 58 abnormal samples) consecutive liquid-based cytology (LBC) samples were analysed. The observed sensitivity and specificity to distinguish normal and abnormal samples was 100%. We observed slight incompatibility in the evaluation of the type of abnormality. The use of ANN is promising for increasing the effectiveness of cervical screening. The low cost of neural network usage further increases the potential areas of application of the presented method. Further refinement of neural networks on a larger sample size is required to evaluate the software. Termedia Publishing House 2019-10-31 2019 /pmc/articles/PMC6883966/ /pubmed/31798334 http://dx.doi.org/10.5114/wo.2019.85617 Text en Copyright: © 2019 Termedia Sp. z o. o. http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license. |
spellingShingle | Original Paper Lasyk, Łukasz Barbasz, Jakub Żuk, Paweł Prusaczyk, Artur Włodarczyk, Tomasz Prokurat, Ewa Olszewski, Wojciech Bidziński, Mariusz Baszuk, Piotr Gronwald, Jacek An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer |
title | An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer |
title_full | An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer |
title_fullStr | An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer |
title_full_unstemmed | An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer |
title_short | An evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer |
title_sort | evaluation of the construction of the device along with the software for digital archiving, sending the data, and supporting the diagnosis of cervical cancer |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883966/ https://www.ncbi.nlm.nih.gov/pubmed/31798334 http://dx.doi.org/10.5114/wo.2019.85617 |
work_keys_str_mv | AT lasykłukasz anevaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT barbaszjakub anevaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT zukpaweł anevaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT prusaczykartur anevaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT włodarczyktomasz anevaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT prokuratewa anevaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT olszewskiwojciech anevaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT bidzinskimariusz anevaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT baszukpiotr anevaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT gronwaldjacek anevaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT lasykłukasz evaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT barbaszjakub evaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT zukpaweł evaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT prusaczykartur evaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT włodarczyktomasz evaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT prokuratewa evaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT olszewskiwojciech evaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT bidzinskimariusz evaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT baszukpiotr evaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer AT gronwaldjacek evaluationoftheconstructionofthedevicealongwiththesoftwarefordigitalarchivingsendingthedataandsupportingthediagnosisofcervicalcancer |