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The Impact of Pathway Database Choice on Statistical Enrichment Analysis and Predictive Modeling

Pathway-centric approaches are widely used to interpret and contextualize -omics data. However, databases contain different representations of the same biological pathway, which may lead to different results of statistical enrichment analysis and predictive models in the context of precision medicin...

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Detalles Bibliográficos
Autores principales:	Mubeen, Sarah, Hoyt, Charles Tapley, Gemünd, André, Hofmann-Apitius, Martin, Fröhlich, Holger, Domingo-Fernández, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883970/ https://www.ncbi.nlm.nih.gov/pubmed/31824580 http://dx.doi.org/10.3389/fgene.2019.01203

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