Cargando…
Intrathecal, Not Systemic Inflammation Is Correlated With Multiple Sclerosis Severity, Especially in Progressive Multiple Sclerosis
Objective: To test the hypothesis that Multiple Sclerosis (MS) patients have increased peripheral inflammation compared to healthy donors and that this systemic activation of the immune system, reflected by acute phase reactants (APRs) measured in the blood, contributes to intrathecal inflammation,...
Autores principales: | Milstein, Joshua L., Barbour, Christopher R., Jackson, Kayla, Kosa, Peter, Bielekova, Bibiana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884093/ https://www.ncbi.nlm.nih.gov/pubmed/31824409 http://dx.doi.org/10.3389/fneur.2019.01232 |
Ejemplares similares
-
Extensive Healthy Donor Age/Gender Adjustments and Propensity Score Matching Reveal Physiology of Multiple Sclerosis Through Immunophenotyping
por: Hannikainen, Paavali A., et al.
Publicado: (2020) -
Insufficient disease inhibition by intrathecal rituximab in progressive multiple sclerosis
por: Komori, Mika, et al.
Publicado: (2016) -
Smartphone Level Test Measures Disability in Several Neurological Domains for Patients With Multiple Sclerosis
por: Boukhvalova, Alexandra K., et al.
Publicado: (2019) -
Current Status and Future Opportunities in Modeling Clinical Characteristics of Multiple Sclerosis
por: Liu, Joshua, et al.
Publicado: (2022) -
Molecular models of multiple sclerosis severity identify heterogeneity of pathogenic mechanisms
por: Kosa, Peter, et al.
Publicado: (2022)