Cargando…

Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes

Abstract: Pancreatitis, a complex disease influenced by both genetic and environmental factors, often leads to metabolic sequelae (such as exocrine pancreatic dysfunction and new-onset diabetes). Several trillion micro-organisms inhabit the gastrointestinal tract, and this community plays an importa...

Descripción completa

Detalles Bibliográficos
Autor principal: Petrov, Maxim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884355/
https://www.ncbi.nlm.nih.gov/pubmed/31609744
http://dx.doi.org/10.14309/ctg.0000000000000086
_version_ 1783474533874794496
author Petrov, Maxim S.
author_facet Petrov, Maxim S.
author_sort Petrov, Maxim S.
collection PubMed
description Abstract: Pancreatitis, a complex disease influenced by both genetic and environmental factors, often leads to metabolic sequelae (such as exocrine pancreatic dysfunction and new-onset diabetes). Several trillion micro-organisms inhabit the gastrointestinal tract, and this community plays an important role in the regulation of functions of not only the gut but also the pancreas. Studies to parse the underlying contributions of the gut microbiota to metabolic sequelae of pancreatitis will offer important translational insights with a view to preventing exocrine pancreatic dysfunction and new-onset diabetes after pancreatitis.
format Online
Article
Text
id pubmed-6884355
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Wolters Kluwer
record_format MEDLINE/PubMed
spelling pubmed-68843552019-12-24 Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes Petrov, Maxim S. Clin Transl Gastroenterol Editorial Abstract: Pancreatitis, a complex disease influenced by both genetic and environmental factors, often leads to metabolic sequelae (such as exocrine pancreatic dysfunction and new-onset diabetes). Several trillion micro-organisms inhabit the gastrointestinal tract, and this community plays an important role in the regulation of functions of not only the gut but also the pancreas. Studies to parse the underlying contributions of the gut microbiota to metabolic sequelae of pancreatitis will offer important translational insights with a view to preventing exocrine pancreatic dysfunction and new-onset diabetes after pancreatitis. Wolters Kluwer 2019-10-11 /pmc/articles/PMC6884355/ /pubmed/31609744 http://dx.doi.org/10.14309/ctg.0000000000000086 Text en © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Editorial
Petrov, Maxim S.
Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes
title Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes
title_full Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes
title_fullStr Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes
title_full_unstemmed Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes
title_short Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes
title_sort metabolic trifecta after pancreatitis: exocrine pancreatic dysfunction, altered gut microbiota, and new-onset diabetes
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884355/
https://www.ncbi.nlm.nih.gov/pubmed/31609744
http://dx.doi.org/10.14309/ctg.0000000000000086
work_keys_str_mv AT petrovmaxims metabolictrifectaafterpancreatitisexocrinepancreaticdysfunctionalteredgutmicrobiotaandnewonsetdiabetes