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Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes
Abstract: Pancreatitis, a complex disease influenced by both genetic and environmental factors, often leads to metabolic sequelae (such as exocrine pancreatic dysfunction and new-onset diabetes). Several trillion micro-organisms inhabit the gastrointestinal tract, and this community plays an importa...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Wolters Kluwer
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884355/ https://www.ncbi.nlm.nih.gov/pubmed/31609744 http://dx.doi.org/10.14309/ctg.0000000000000086 |
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author | Petrov, Maxim S. |
author_facet | Petrov, Maxim S. |
author_sort | Petrov, Maxim S. |
collection | PubMed |
description | Abstract: Pancreatitis, a complex disease influenced by both genetic and environmental factors, often leads to metabolic sequelae (such as exocrine pancreatic dysfunction and new-onset diabetes). Several trillion micro-organisms inhabit the gastrointestinal tract, and this community plays an important role in the regulation of functions of not only the gut but also the pancreas. Studies to parse the underlying contributions of the gut microbiota to metabolic sequelae of pancreatitis will offer important translational insights with a view to preventing exocrine pancreatic dysfunction and new-onset diabetes after pancreatitis. |
format | Online Article Text |
id | pubmed-6884355 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer |
record_format | MEDLINE/PubMed |
spelling | pubmed-68843552019-12-24 Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes Petrov, Maxim S. Clin Transl Gastroenterol Editorial Abstract: Pancreatitis, a complex disease influenced by both genetic and environmental factors, often leads to metabolic sequelae (such as exocrine pancreatic dysfunction and new-onset diabetes). Several trillion micro-organisms inhabit the gastrointestinal tract, and this community plays an important role in the regulation of functions of not only the gut but also the pancreas. Studies to parse the underlying contributions of the gut microbiota to metabolic sequelae of pancreatitis will offer important translational insights with a view to preventing exocrine pancreatic dysfunction and new-onset diabetes after pancreatitis. Wolters Kluwer 2019-10-11 /pmc/articles/PMC6884355/ /pubmed/31609744 http://dx.doi.org/10.14309/ctg.0000000000000086 Text en © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Editorial Petrov, Maxim S. Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes |
title | Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes |
title_full | Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes |
title_fullStr | Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes |
title_full_unstemmed | Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes |
title_short | Metabolic Trifecta After Pancreatitis: Exocrine Pancreatic Dysfunction, Altered Gut Microbiota, and New-Onset Diabetes |
title_sort | metabolic trifecta after pancreatitis: exocrine pancreatic dysfunction, altered gut microbiota, and new-onset diabetes |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884355/ https://www.ncbi.nlm.nih.gov/pubmed/31609744 http://dx.doi.org/10.14309/ctg.0000000000000086 |
work_keys_str_mv | AT petrovmaxims metabolictrifectaafterpancreatitisexocrinepancreaticdysfunctionalteredgutmicrobiotaandnewonsetdiabetes |