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Enhanced lysosomal degradation maintains the quiescent state of neural stem cells

Quiescence is important for sustaining neural stem cells (NSCs) in the adult brain over the lifespan. Lysosomes are digestive organelles that degrade membrane receptors after they undergo endolysosomal membrane trafficking. Enlarged lysosomes are present in quiescent NSCs (qNSCs) in the subventricul...

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Detalles Bibliográficos
Autores principales:	Kobayashi, Taeko, Piao, Wenhui, Takamura, Toshiya, Kori, Hiroshi, Miyachi, Hitoshi, Kitano, Satsuki, Iwamoto, Yumiko, Yamada, Mayumi, Imayoshi, Itaru, Shioda, Seiji, Ballabio, Andrea, Kageyama, Ryoichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884460/ https://www.ncbi.nlm.nih.gov/pubmed/31784517 http://dx.doi.org/10.1038/s41467-019-13203-4

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