Cargando…

SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals

Amphisomes are organelles of the autophagy pathway that result from the fusion of autophagosomes with late endosomes. While biogenesis of autophagosomes and late endosomes occurs continuously at axon terminals, non-degradative roles of autophagy at boutons are barely described. Here, we show that in...

Descripción completa

Detalles Bibliográficos
Autores principales: Andres-Alonso, Maria, Ammar, Mohamed Raafet, Butnaru, Ioana, Gomes, Guilherme M., Acuña Sanhueza, Gustavo, Raman, Rajeev, Yuanxiang, PingAn, Borgmeyer, Maximilian, Lopez-Rojas, Jeffrey, Raza, Syed Ahsan, Brice, Nicola, Hausrat, Torben J., Macharadze, Tamar, Diaz-Gonzalez, Silvia, Carlton, Mark, Failla, Antonio Virgilio, Stork, Oliver, Schweizer, Michaela, Gundelfinger, Eckart D., Kneussel, Matthias, Spilker, Christina, Karpova, Anna, Kreutz, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884526/
https://www.ncbi.nlm.nih.gov/pubmed/31784514
http://dx.doi.org/10.1038/s41467-019-13224-z