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Isodeoxyelephantopin, a Sesquiterpene Lactone Induces ROS Generation, Suppresses NF-κB Activation, Modulates LncRNA Expression and Exhibit Activities Against Breast Cancer

The sesquiterpene lactones, Isodeoxyelephantopin (IDET) and Deoxyelephantopin (DET) are known to exhibit activities against some cancer types. The activities of these lactones against breast cancer and the molecular bases is not known. We examined the efficacy of lactones in breast cancer preclinica...

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Detalles Bibliográficos
Autores principales: Verma, Sumit S., Rai, Vipin, Awasthee, Nikee, Dhasmana, Anupam, Rajalaksmi, Dhanya S, Nair, Mangalam S., Gupta, Subash C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884568/
https://www.ncbi.nlm.nih.gov/pubmed/31784542
http://dx.doi.org/10.1038/s41598-019-52971-3