Cargando…
Fractionated head and neck irradiation impacts taste progenitors, differentiated taste cells, and Wnt/β-catenin signaling in adult mice
Head and neck cancer patients receiving conventional repeated, low dose radiotherapy (fractionated IR) suffer from taste dysfunction that can persist for months and often years after treatment. To understand the mechanisms underlying functional taste loss, we established a fractionated IR mouse mode...
Autores principales: | Gaillard, Dany, Shechtman, Lauren A., Millar, Sarah E., Barlow, Linda A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884601/ https://www.ncbi.nlm.nih.gov/pubmed/31784592 http://dx.doi.org/10.1038/s41598-019-54216-9 |
Ejemplares similares
-
β-catenin is required for taste bud cell renewal and behavioral taste perception in adult mice
por: Gaillard, Dany, et al.
Publicado: (2017) -
β-Catenin Signaling Biases Multipotent Lingual Epithelial Progenitors to Differentiate and Acquire Specific Taste Cell Fates
por: Gaillard, Dany, et al.
Publicado: (2015) -
Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function
por: Golden, Erin J, et al.
Publicado: (2021) -
Cyclophosphamide and the taste system: Effects of dose fractionation and amifostine on taste cell renewal
por: Delay, Eugene R., et al.
Publicado: (2019) -
FGF Signaling Regulates the Number of Posterior Taste Papillae by Controlling Progenitor Field Size
por: Petersen, Camille I., et al.
Publicado: (2011)