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Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice
Diabetes worsens atherosclerosis progression and leads to a defect in repair of arteries after cholesterol reduction, a process termed regression. Empagliflozin reduces blood glucose levels via inhibition of the sodium glucose cotransporter 2 (SGLT-2) in the kidney and has been shown to lead to a ma...
Autores principales: | Pennig, Jan, Scherrer, Philipp, Gissler, Mark Colin, Anto-Michel, Nathaly, Hoppe, Natalie, Füner, Lisa, Härdtner, Carmen, Stachon, Peter, Wolf, Dennis, Hilgendorf, Ingo, Mullick, Adam, Bode, Christoph, Zirlik, Andreas, Goldberg, Ira J., Willecke, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884628/ https://www.ncbi.nlm.nih.gov/pubmed/31784656 http://dx.doi.org/10.1038/s41598-019-54224-9 |
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