Cargando…
Inhibition of microglial activation in rats attenuates paraventricular nucleus inflammation in Gαi(2) protein‐dependent, salt‐sensitive hypertension
NEW FINDINGS: • What is the central question of this study? We hypothesized that central inflammatory processes that involve activation of microglia and astrocytes contribute to the development of Gαi(2) protein‐dependent, salt‐sensitive hypertension. • What is the main finding and its importance? T...
Autores principales: | Moreira, Jesse D., Chaudhary, Parul, Frame, Alissa A., Puleo, Franco, Nist, Kayla M., Abkin, Eric A., Moore, Tara L., George, Jonique C., Wainford, Richard D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884700/ https://www.ncbi.nlm.nih.gov/pubmed/31631436 http://dx.doi.org/10.1113/EP087924 |
Ejemplares similares
-
Natriuresis During an Acute Intravenous Sodium Chloride Infusion in Conscious Sprague Dawley Rats Is Mediated by a Blood Pressure-Independent α(1)-Adrenoceptor-Mediated Mechanism
por: Frame, Alissa A., et al.
Publicado: (2022) -
GNAI2 polymorphic variance associates with salt sensitivity of blood pressure in the Genetic Epidemiology Network of Salt Sensitivity study
por: Zhang, Xiaoling, et al.
Publicado: (2018) -
An exploratory analysis of comparative plasma metabolomic and lipidomic profiling in salt-sensitive and salt-resistant individuals from The Dietary Approaches to Stop Hypertension Sodium Trial
por: Chaudhary, Parul, et al.
Publicado: (2021) -
Inhibition of cGAS in Paraventricular Nucleus Attenuates Hypertensive Heart Injury Via Regulating Microglial Autophagy
por: Han, Chengzhi, et al.
Publicado: (2022) -
Sensory Afferent Renal Nerve Activated Gαi(2) Subunit Proteins Mediate the Natriuretic, Sympathoinhibitory and Normotensive Responses to Peripheral Sodium Challenges
por: Moreira, Jesse D., et al.
Publicado: (2021)