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Papillome inversé: à propos de 13 cas au Service d’Oto-Rhino-Laryngologie du Centre Hospitalier National Universitaire de Fann
INTRODUCTION: Inverted Papilloma (IP) is a rare benign tumour of the nose and paranasal sinuses histologically characterized by invagination of the outer layer of the epithelium in the underlying chorion. Its most distinctive feature is a strong local aggressiveness, a tendency to recur and an unpre...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884737/ https://www.ncbi.nlm.nih.gov/pubmed/31819787 http://dx.doi.org/10.11604/pamj.2019.34.71.19888 |
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author | Ndiaye, Moustapha Ndiaye, Ciré Diouf, Mame Sanou Sarr, Ndèye Oumy Sy, Abdou Ndiaye, Malick Tall, Abdourahmane |
author_facet | Ndiaye, Moustapha Ndiaye, Ciré Diouf, Mame Sanou Sarr, Ndèye Oumy Sy, Abdou Ndiaye, Malick Tall, Abdourahmane |
author_sort | Ndiaye, Moustapha |
collection | PubMed |
description | INTRODUCTION: Inverted Papilloma (IP) is a rare benign tumour of the nose and paranasal sinuses histologically characterized by invagination of the outer layer of the epithelium in the underlying chorion. Its most distinctive feature is a strong local aggressiveness, a tendency to recur and an unpredictable risk of association with epidermoid carcinoma. The purpose of this study was to report the epidemiological, clinical, paraclinical data as well as to assess the outcomes of endoscopic endonasal surgery. METHODS: We conducted a retrospective study on a series of 13 patients whose data were collected in the Oto-Rhino-Laryngology at the National University Hospital Center of Fann, from 1(st) January 2012 to 31(st) December 2017. All patients followed up for inverted papilloma confirmed by anathomopathological examination were included in the study. RESULTS: The average age of patients was 44 years, the sex-ratio was 2.25. All patients had nasal obstruction; 53% of them had rhinorrhea followed by epistaxis in 30% of cases. Right-sided symptoms were reported by 69% of patients, left-sided symptoms by 23% and bilateral symptoms by 7% of patients. Anterior rhinoscopy showed endonasal mass in all patients. All patients underwent CT scan; the MRI was performed in a single patient. Endoscopic resection of IP was performed in 10 patients (76.9%) while external approach was used in 23% of cases. Surgery helped to clarify where the tumor had originated: in 46% of cases in the maxillary sinus, in 15% in the lower nasal turbinate, in 15% in the mid-turbinate, in 7% in the ethmoid bulla and in 7% in the lateral wall of the nasal fossa. One patient had recurrence after an average period of 26 months. Malignant transformation to squamous cell carcinoma occurred in one patient. CONCLUSION: Inverted papilloma is a very aggressive tumor. CT scan is essential to highlight its spread, especially to bone. The advent of endoscopic surgery has revolutionised treatment, providing excellent results. But, there is nevertheless a risk of recurrence after surgery which motivates an indication for long term monitoring. |
format | Online Article Text |
id | pubmed-6884737 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-68847372019-12-09 Papillome inversé: à propos de 13 cas au Service d’Oto-Rhino-Laryngologie du Centre Hospitalier National Universitaire de Fann Ndiaye, Moustapha Ndiaye, Ciré Diouf, Mame Sanou Sarr, Ndèye Oumy Sy, Abdou Ndiaye, Malick Tall, Abdourahmane Pan Afr Med J Research INTRODUCTION: Inverted Papilloma (IP) is a rare benign tumour of the nose and paranasal sinuses histologically characterized by invagination of the outer layer of the epithelium in the underlying chorion. Its most distinctive feature is a strong local aggressiveness, a tendency to recur and an unpredictable risk of association with epidermoid carcinoma. The purpose of this study was to report the epidemiological, clinical, paraclinical data as well as to assess the outcomes of endoscopic endonasal surgery. METHODS: We conducted a retrospective study on a series of 13 patients whose data were collected in the Oto-Rhino-Laryngology at the National University Hospital Center of Fann, from 1(st) January 2012 to 31(st) December 2017. All patients followed up for inverted papilloma confirmed by anathomopathological examination were included in the study. RESULTS: The average age of patients was 44 years, the sex-ratio was 2.25. All patients had nasal obstruction; 53% of them had rhinorrhea followed by epistaxis in 30% of cases. Right-sided symptoms were reported by 69% of patients, left-sided symptoms by 23% and bilateral symptoms by 7% of patients. Anterior rhinoscopy showed endonasal mass in all patients. All patients underwent CT scan; the MRI was performed in a single patient. Endoscopic resection of IP was performed in 10 patients (76.9%) while external approach was used in 23% of cases. Surgery helped to clarify where the tumor had originated: in 46% of cases in the maxillary sinus, in 15% in the lower nasal turbinate, in 15% in the mid-turbinate, in 7% in the ethmoid bulla and in 7% in the lateral wall of the nasal fossa. One patient had recurrence after an average period of 26 months. Malignant transformation to squamous cell carcinoma occurred in one patient. CONCLUSION: Inverted papilloma is a very aggressive tumor. CT scan is essential to highlight its spread, especially to bone. The advent of endoscopic surgery has revolutionised treatment, providing excellent results. But, there is nevertheless a risk of recurrence after surgery which motivates an indication for long term monitoring. The African Field Epidemiology Network 2019-10-04 /pmc/articles/PMC6884737/ /pubmed/31819787 http://dx.doi.org/10.11604/pamj.2019.34.71.19888 Text en © Moustapha Ndiaye et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Ndiaye, Moustapha Ndiaye, Ciré Diouf, Mame Sanou Sarr, Ndèye Oumy Sy, Abdou Ndiaye, Malick Tall, Abdourahmane Papillome inversé: à propos de 13 cas au Service d’Oto-Rhino-Laryngologie du Centre Hospitalier National Universitaire de Fann |
title | Papillome inversé: à propos de 13 cas au Service d’Oto-Rhino-Laryngologie du Centre Hospitalier National Universitaire de Fann |
title_full | Papillome inversé: à propos de 13 cas au Service d’Oto-Rhino-Laryngologie du Centre Hospitalier National Universitaire de Fann |
title_fullStr | Papillome inversé: à propos de 13 cas au Service d’Oto-Rhino-Laryngologie du Centre Hospitalier National Universitaire de Fann |
title_full_unstemmed | Papillome inversé: à propos de 13 cas au Service d’Oto-Rhino-Laryngologie du Centre Hospitalier National Universitaire de Fann |
title_short | Papillome inversé: à propos de 13 cas au Service d’Oto-Rhino-Laryngologie du Centre Hospitalier National Universitaire de Fann |
title_sort | papillome inversé: à propos de 13 cas au service d’oto-rhino-laryngologie du centre hospitalier national universitaire de fann |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884737/ https://www.ncbi.nlm.nih.gov/pubmed/31819787 http://dx.doi.org/10.11604/pamj.2019.34.71.19888 |
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