Influenza A virus hemagglutinin mutations associated with use of neuraminidase inhibitors correlate with decreased inhibition by anti-influenza antibodies

BACKGROUND: Vaccination and the use of neuraminidase inhibitors (NAIs) are currently the front lines of defense against seasonal influenza. The activity of influenza vaccines and antivirals drugs such as the NAIs can be affected by mutations in the influenza hemagglutinin (HA) protein. Numerous HA s...

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Detalles Bibliográficos
Autores principales: Ilyushina, Natalia A., Komatsu, Takashi E., Ince, William L., Donaldson, Eric F., Lee, Nicolette, O’Rear, Julian J., Donnelly, Raymond P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884823/
https://www.ncbi.nlm.nih.gov/pubmed/31783761
http://dx.doi.org/10.1186/s12985-019-1258-x

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