Cargando…

Restriction factors in human retrovirus infections and the unprecedented case of CIITA as link of intrinsic and adaptive immunity against HTLV-1

BACKGROUND: Immunity against pathogens evolved through complex mechanisms that only for sake of simplicity are defined as innate immunity and adaptive immunity. Indeed innate and adaptive immunity are strongly intertwined each other during evolution. The complexity is further increased by intrinsic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Forlani, Greta, Shallak, Mariam, Ramia, Elise, Tedeschi, Alessandra, Accolla, Roberto S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884849/ https://www.ncbi.nlm.nih.gov/pubmed/31783769 http://dx.doi.org/10.1186/s12977-019-0498-6

Ejemplares similares

The NLR member CIITA: Master controller of adaptive and intrinsic immunity and unexpected tool in cancer immunotherapy
por: Forlani, Greta, et al.
Publicado: (2023)

CIITA-Driven MHC Class II Expressing Tumor Cells as Antigen Presenting Cell Performers: Toward the Construction of an Optimal Anti-tumor Vaccine
por: Accolla, Roberto S., et al.
Publicado: (2019)

The MHC-II transactivator CIITA, a restriction factor against oncogenic HTLV-1 and HTLV-2 retroviruses: similarities and differences in the inhibition of Tax-1 and Tax-2 viral transactivators
por: Forlani, Greta, et al.
Publicado: (2013)

Unveiling the Hidden Treasury: CIITA-Driven MHC Class II Expression in Tumor Cells to Dig up the Relevant Repertoire of Tumor Antigens for Optimal Stimulation of Tumor Specific CD4+ T Helper Cells
por: Forlani, Greta, et al.
Publicado: (2020)

Dual cytoplasmic and nuclear localization of HTLV-1-encoded HBZ protein is a unique feature of adult T-cell leukemia
por: Forlani, Greta, et al.
Publicado: (2021)

Protective anti-tumor vaccination against glioblastoma expressing the MHC class II transactivator CIITA
por: Celesti, Fabrizio, et al.
Publicado: (2023)

HTLV-1 Infection and Pathogenesis: New Insights from Cellular and Animal Models
por: Forlani, Greta, et al.
Publicado: (2021)

Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication
por: Orlandi, Chiara, et al.
Publicado: (2011)

The MHC Class II transactivator CIITA inhibits Tax-1-mediated HTLV-1 expression and NF-kB activation
por: Abdallah, Rawan, et al.
Publicado: (2014)

MHC class II transactivator CIITA inhibits Tax-2-mediated HTLV-2 LTR transactivation and viral replication by binding to, and affecting Tax-2 intracellular localization
por: Orlandi, Chiara, et al.
Publicado: (2011)

The MHC-II transactivator CIITA inhibits Tat function and HIV-1 replication in human myeloid cells
por: Forlani, Greta, et al.
Publicado: (2016)

Tripartite Motif 22 and Class II Transactivator Restriction Factors: Unveiling Their Concerted Action against Retroviruses
por: Forlani, Greta, et al.
Publicado: (2017)

The endogenous HBZ interactome in ATL leukemic cells reveals an unprecedented complexity of host interacting partners involved in RNA splicing
por: Shallak, Mariam, et al.
Publicado: (2022)

The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T-Cell Lymphotropic Virus Type 1
por: Tosi, Giovanna, et al.
Publicado: (2011)

CIITA-Transduced Glioblastoma Cells Uncover a Rich Repertoire of Clinically Relevant Tumor-Associated HLA-II Antigens
por: Forlani, Greta, et al.
Publicado: (2021)

The MHC Class II transactivator CIITA inhibits the persistent activation of NF-kB by Tax-1
por: Forlani, Greta, et al.
Publicado: (2015)

HTLV-1 HBZ Viral Protein: A Key Player in HTLV-1 Mediated Diseases
por: Baratella, Marco, et al.
Publicado: (2017)

HTLV-1 HBZ Protein Resides Exclusively in the Cytoplasm of Infected Cells in Asymptomatic Carriers and HAM/TSP Patients
por: Forlani, Greta, et al.
Publicado: (2019)

Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP)
por: Baratella, Marco, et al.
Publicado: (2017)

Fowlpoxvirus recombinants coding for the CIITA gene increase the expression of endogenous MHC-II and Fowlpox Gag/Pro and Env SIV transgenes
por: Bissa, Massimiliano, et al.
Publicado: (2018)

A Panel of Eight miRNAs Is Deregulated in HTLV-2 Infected PBMCs and BJABGu Cell Line
por: Pilotti, Elisabetta, et al.
Publicado: (2022)

Is the HTLV-1 Retrovirus Targeted by Host Restriction Factors?
por: Carcone, Auriane, et al.
Publicado: (2022)

A dual defensive role of CIITA against retroviral infections
por: Tosi, Giovanna, et al.
Publicado: (2006)

Localization, quantification and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL
por: Raval, Goutham U, et al.
Publicado: (2015)

Localization, quantization and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL
por: Raval, Goutham U, et al.
Publicado: (2015)

Localization, quantization and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATL
por: Raval, Goutham U, et al.
Publicado: (2015)

The discovery of the first human retrovirus: HTLV-1 and HTLV-2
por: Gallo, Robert C
Publicado: (2005)

The Road to HTLV-1-Induced Leukemia by Following the Subcellular Localization of HTLV-1-Encoded HBZ Protein
por: Accolla, Roberto S.
Publicado: (2022)

SIRT1 links CIITA deacetylation to MHC II activation
por: Wu, Xiaoyan, et al.
Publicado: (2011)

Boosting the MHC Class II-Restricted Tumor Antigen Presentation to CD4+ T Helper Cells: A Critical Issue for Triggering Protective Immunity and Re-Orienting the Tumor Microenvironment Toward an Anti-Tumor State
por: Accolla, Roberto S., et al.
Publicado: (2014)

Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses
por: Simonis, Nicolas, et al.
Publicado: (2012)

CRISPR Genome Editing Applied to the Pathogenic Retrovirus HTLV-1
por: Panfil, Amanda R., et al.
Publicado: (2020)

Retroviruses, retroelements and their restrictions
por: Koito, Atsushi, et al.
Publicado: (2013)

Mucosal immune response after the booster dose of the BNT162b2 COVID-19 vaccine
por: Azzi, Lorenzo, et al.
Publicado: (2023)

12(th )international conference on human retrovirology: HTLV and related retroviruses
por: Lairmore, Michael D, et al.
Publicado: (2005)

The 15th International Conference on Human Retroviruses: HTLV and Related Viruses
por: Vandamme, Annemie, et al.
Publicado: (2011)

16th International Conference on Human Retrovirology: HTLV and Related Retroviruses
por: Barbeau, Benoit
Publicado: (2014)

Reply to the Letter to the Editor: “Importance of nasal secretions in the evaluation of mucosal immunity elicited by mRNA BNT162b2 COVID-19 vaccine” by Francavilla B et al.: Lack of a strong oral mucosal immune response: rethinking the route of COVID-19 vaccine boost administration?
por: Azzi, Lorenzo, et al.
Publicado: (2022)

Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunity
por: Dittmer, Ulf, et al.
Publicado: (2019)

Nanotechnology based strategies for HIV-1 and HTLV-1 retroviruses gene detection
por: Mozhgani, Sayed-Hamidreza, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fkcc3c9igdr97valhkgdnne8qo