Cargando…

Comparative metabolomic analysis reveals the variations in taxoids and flavonoids among three Taxus species

BACKGROUND: Trees of the genus Taxus are highly valuable medicinal plants with multiple pharmacological effects on various cancer treatments. Paclitaxel from Taxus trees is an efficient and widely used anticancer drug, however, the accumulation of taxoids and other active ingredients can vary greatl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Ting, Luo, Xiujun, Zhang, Chengchao, Xu, Xinyun, Yu, Chunna, Jiang, Zhifang, Zhang, Lei, Yuan, Huwei, Zheng, Bingsong, Pi, Erxu, Shen, Chenjia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884900/ https://www.ncbi.nlm.nih.gov/pubmed/31783790 http://dx.doi.org/10.1186/s12870-019-2146-7

Ejemplares similares

Omic analysis of the endangered Taxaceae species Pseudotaxus chienii revealed the differences in taxol biosynthesis pathway between Pseudotaxus and Taxus yunnanensis trees
por: Yu, Chunna, et al.
Publicado: (2021)

Comparative metabolomics reveals the metabolic variations between two endangered Taxus species (T. fuana and T. yunnanensis) in the Himalayas
por: Yu, Chunna, et al.
Publicado: (2018)

Transcriptome analyses provide insights into the expression pattern and sequence similarity of several taxol biosynthesis-related genes in three Taxus species
por: Zhou, Ting, et al.
Publicado: (2019)

Análisis de taxoides (taxus globosa schlech)
por: Ramos Lobato, Nancy Aurelia
Publicado: (1998)

Profiling of Taxoid Compounds in Plant Cell Cultures of Different Species of Yew (Taxus spp.)
por: Kochkin, Dmitry V., et al.
Publicado: (2023)

Role of female-predominant MYB39-bHLH13 complex in sexually dimorphic accumulation of taxol in Taxus media
por: Yu, Chunna, et al.
Publicado: (2022)

Multidrug Resistance Reversal Activity of Taxoids from Taxus cuspidate in KB‐C2 and 2780AD Cells
por: Kobayashi, Jun'ichi, et al.
Publicado: (2000)

Succinyl-proteome profiling of a high taxol containing hybrid Taxus species (Taxus × media) revealed involvement of succinylation in multiple metabolic pathways
por: Shen, Chenjia, et al.
Publicado: (2016)

Effect of Methyl Jasmonate on the Growth and Biosynthesis of C13- and C14-Hydroxylated Taxoids in the Cell Culture of Yew (Taxus wallichiana Zucc.) of Different Ages
por: Demidova, Elena, et al.
Publicado: (2023)

Flavonoid Components, Distribution, and Biological Activities in Taxus: A review
por: Wei, Qiang, et al.
Publicado: (2023)

Investigation of bioactivities of Taxus chinensis, Taxus cuspidata, and Taxus × media by gas chromatography-mass spectrometry
por: Zhang, Shuqiang, et al.
Publicado: (2021)

Mass spectrometry imaging and single-cell transcriptional profiling reveal the tissue-specific regulation of bioactive ingredient biosynthesis in Taxus leaves
por: Zhan, Xiaori, et al.
Publicado: (2023)

Quest for Efficacious Next-Generation Taxoid Anticancer Agents and Their Tumor-Targeted Delivery
por: Ojima, Iwao, et al.
Publicado: (2018)

Synthesis and Cytotoxicity of 7,9-O-Linked Macrocyclic C-Seco Taxoids
por: Zhao, Yu, et al.
Publicado: (2019)

Characterisation of a navelbine-resistant bladder carcinoma cell line cross-resistant to taxoids.
por: Debal, V., et al.
Publicado: (1994)

A comparative metabolomics analysis of the components of heartwood and sapwood in Taxus chinensis (Pilger) Rehd.
por: Shao, Fenjuan, et al.
Publicado: (2019)

Analysis of the utilization value of different tissues of Taxus×Media based on metabolomics and antioxidant activity
por: Li, Meng, et al.
Publicado: (2023)

Genome-wide identification of CAMTA gene family members in Medicago truncatula and their expression during root nodule symbiosis and hormone treatments
por: Yang, Yanjun, et al.
Publicado: (2015)

DNA and Flavonoids Leach out from Active Nuclei of Taxus and Tsuga after Extreme Climate Stresses
por: Feucht, Walter, et al.
Publicado: (2015)

Chemical Constituents from Streblus taxoides Wood with Their Antibacterial and Antityrosinase Activities Plus in Silico Study
por: Parndaeng, Kedsaraporn, et al.
Publicado: (2023)

Quantitative succinyl-proteome profiling of Chinese hickory (Carya cathayensis) during the grafting process
por: Yuan, Huwei, et al.
Publicado: (2019)

Effects of Seasonal Changes on Chlorophyll Fluorescence and Physiological Characteristics in the Two Taxus Species
por: Wang, Tao, et al.
Publicado: (2023)

Taxus – The Panacea for Cancer Treatment
por: Manish, Lavhle, et al.
Publicado: (2005)

Comparative Proteomic Analysis of the Graft Unions in Hickory (Carya cathayensis) Provides Insights into Response Mechanisms to Grafting Process
por: Xu, Dongbin, et al.
Publicado: (2017)

Design, Synthesis, and Biological Evaluations of Tumor-Targeting Dual-Warhead Conjugates for a Taxoid–Camptothecin Combination Chemotherapy
por: Vineberg, Jacob G., et al.
Publicado: (2014)

The complete chloroplast genome sequence of Taxus yunnanensis
por: Geng, Yunfen, et al.
Publicado: (2020)

Development and characterization of microsatellite loci in the endangered species Taxus wallichiana (Taxaceae)(1)
por: Gajurel, Jyoti Prasad, et al.
Publicado: (2013)

Quality evaluation of compounds in leaves of six Taxus species based on UPLC-MS/MS and chemometrics
por: Cai, Qingzhu, et al.
Publicado: (2023)

A fatal case of Taxus poisoning
por: TRANCA, SEBASTIAN, et al.
Publicado: (2013)

Effects of LED supplemental lighting on the growth and metabolomic profile of Taxus baccata cultivated in a smart greenhouse
por: Chiocchio, Ilaria, et al.
Publicado: (2022)

The Taxus genome provides insights into paclitaxel biosynthesis
por: Xiong, Xingyao, et al.
Publicado: (2021)

Docetaxel (Taxotere), a novel taxoid, in the treatment of advanced colorectal carcinoma: an EORTC Early Clinical Trials Group Study.
por: Sternberg, C. N., et al.
Publicado: (1994)

A Comparison of the Flavonoid Biosynthesis Mechanisms of Dendrobium Species by Analyzing the Transcriptome and Metabolome
por: Liu, Sian, et al.
Publicado: (2022)

A comparative metabolomics investigation of flavonoid variation in faba bean flowers
por: Elessawy, Fatma M., et al.
Publicado: (2023)

Study of the Pollen Grain Metabolome under Deposition of Nitrogen and Phosphorus in Taxus baccata L. and Juniperus communis L.
por: Pers-Kamczyc, Emilia, et al.
Publicado: (2022)

Taxoid profile in endophytic fungi isolated from Corylus avellana, introduces potential source for the production of Taxol in semi-synthetic approaches
por: Mohammadi Ballakuti, Narjes, et al.
Publicado: (2022)

New Taxane Diterpenoids from Taxus yunnanensis
por: Hai, Ping, et al.
Publicado: (2014)

Yew (Taxus) intoxication in free-ranging cervids
por: Handeland, Kjell, et al.
Publicado: (2017)

Clinical outcomes between different stent designs with the same polymer and drug: comparison between the Taxus Express and Taxus Liberte stents
por: Son, Jang-Won, et al.
Publicado: (2013)

Transcriptional profile of Taxus chinensis cells in response to methyl jasmonate
por: Li, Shu-tao, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_s2l2pp5ohkmg1nrdoeg5n9d3fa