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Autophagic and endo-lysosomal dysfunction in neurodegenerative disease

Due to their post-mitotic state, metabolic demands and often large polarised morphology, the function and survival of neurons is dependent on an efficient cellular waste clearance system both for generation of materials for metabolic processes and removal of toxic components. It is not surprising th...

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Detalles Bibliográficos
Autores principales: Malik, Bilal R., Maddison, Daniel C., Smith, Gaynor A., Peters, Owen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884906/
https://www.ncbi.nlm.nih.gov/pubmed/31783880
http://dx.doi.org/10.1186/s13041-019-0504-x