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Autophagic and endo-lysosomal dysfunction in neurodegenerative disease
Due to their post-mitotic state, metabolic demands and often large polarised morphology, the function and survival of neurons is dependent on an efficient cellular waste clearance system both for generation of materials for metabolic processes and removal of toxic components. It is not surprising th...
Autores principales: | Malik, Bilal R., Maddison, Daniel C., Smith, Gaynor A., Peters, Owen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884906/ https://www.ncbi.nlm.nih.gov/pubmed/31783880 http://dx.doi.org/10.1186/s13041-019-0504-x |
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