Cargando…
Effects of Dexmedetomidine on the RhoA /ROCK/ Nox4 Signaling Pathway in Renal Fibrosis of Diabetic Rats
OBJECTIVE: To investigate the effects and mechanisms of dexmedetomidine (Dex) on model rats of diabetic nephropathy (DN). METHODS: Rats were divided into NC, model, Dex-L (1μg/ kg), Dex-M (5μg/kg) and Dex-H (10μg/kg) groups. Rats in all groups except in the NC group were injected with streptozotocin...
Autores principales: | Jihua, Chen, Cai, Chen, Xubin, Bao, Yue, Yu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884926/ https://www.ncbi.nlm.nih.gov/pubmed/31844679 http://dx.doi.org/10.1515/med-2019-0105 |
Ejemplares similares
-
Ursolic acid reverses liver fibrosis by inhibiting interactive NOX4/ROS and RhoA/ROCK1 signalling pathways
por: Wan, Sizhe, et al.
Publicado: (2020) -
Interaction Mechanisms Between the NOX4/ROS and RhoA/ROCK1 Signaling Pathways as New Anti- fibrosis Targets of Ursolic Acid in Hepatic Stellate Cells
por: Huang, Chenkai, et al.
Publicado: (2019) -
The RhoA-ROCK pathway in the regulation of T and B cell responses
por: Ricker, Edd, et al.
Publicado: (2016) -
Roles of the RhoA-ROCK Signaling Pathway in the Endothelial H(2)S Production
and Vasodilation in Rat Cerebral Arteries
por: Chen, Shuo, et al.
Publicado: (2022) -
ROCK (RhoA/Rho Kinase) in Cardiovascular–Renal Pathophysiology: A Review of New Advancements
por: Seccia, Teresa M., et al.
Publicado: (2020)