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Effects of Dexmedetomidine on the RhoA /ROCK/ Nox4 Signaling Pathway in Renal Fibrosis of Diabetic Rats

OBJECTIVE: To investigate the effects and mechanisms of dexmedetomidine (Dex) on model rats of diabetic nephropathy (DN). METHODS: Rats were divided into NC, model, Dex-L (1μg/ kg), Dex-M (5μg/kg) and Dex-H (10μg/kg) groups. Rats in all groups except in the NC group were injected with streptozotocin...

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Detalles Bibliográficos
Autores principales: Jihua, Chen, Cai, Chen, Xubin, Bao, Yue, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884926/
https://www.ncbi.nlm.nih.gov/pubmed/31844679
http://dx.doi.org/10.1515/med-2019-0105

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