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Genetic knockout of myosin light chain kinase (MLCK210) prevents cerebral microhemorrhages and attenuates neuroinflammation in a mouse model of vascular cognitive impairment and dementia
The blood-brain barrier (BBB) is critical in maintenance of brain homeostasis, and loss of its functional integrity is a key feature across a broad range of neurological insults. This includes both acute injuries such as traumatic brain injury and stroke, as well as more chronic pathologies associat...
Autores principales: | Braun, David J., Bachstetter, Adam D., Sudduth, Tiffany L., Wilcock, Donna M., Watterson, D. Martin, Van Eldik, Linda J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885026/ https://www.ncbi.nlm.nih.gov/pubmed/31104189 http://dx.doi.org/10.1007/s11357-019-00072-4 |
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