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Palmitic Acid Induces MicroRNA-221 Expression to Decrease Glucose Uptake in HepG2 Cells via the PI3K/AKT/GLUT4 Pathway

Obesity-related insulin resistance and high fatty acid concentrations occur during the development of type 2 diabetes mellitus. The role of high concentrations of plasma-free fatty acids is not fully understood. In this study, palmitic acid (PA, 0.8 mM for 24 h) induced the expression of miR-221 tha...

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Detalles Bibliográficos
Autores principales: Huang, Fang, Chen, Jie, Wang, Jingwen, Zhu, Pingping, Lin, Wenting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885153/
https://www.ncbi.nlm.nih.gov/pubmed/31828133
http://dx.doi.org/10.1155/2019/8171989

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