SOST Deficiency Aggravates Osteoarthritis in Mice by Promoting Sclerosis of Subchondral Bone

As the initial part in the development of osteoarthritis (OA), subchondral bone sclerosis has been considered to be initiated by excess mechanical loading and proven to be correlated to other pathological changes. Sclerostin, which is an essential mechanical stress response protein, is encoded by th...

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Detalles Bibliográficos
Autores principales: Li, Jingyu, Xue, Junjie, Jing, Yan, Wang, Manyi, Shu, Rui, Xu, Hui, Xue, Chaoran, Feng, Jie, Wang, Peiqi, Bai, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885161/
https://www.ncbi.nlm.nih.gov/pubmed/31828128
http://dx.doi.org/10.1155/2019/7623562

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