Short Communication: Interaction of Nerve Growth Factor (NGF) and Vascular Endothelial Growth Factor (VEGF) in Healthy Individuals

NGF and VEGF are known to be involved in different psychiatric diseases. In order to verify hints from basic research that both neurotrophines interact with each other, serum levels of NGF and VEGF were measured in a cohort of 33 healthy individuals and correlated. NGF level was 126.30 pg/mL (±155.4...

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Autores principales: Groh, Adrian, Jahn, Kirsten, Gröschl, Michael, Hillemacher, Thomas, Kornhuber, Johannes, Bleich, Stefan, Frieling, Helge, Heberlein, Annemarie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885270/
https://www.ncbi.nlm.nih.gov/pubmed/31827642
http://dx.doi.org/10.1155/2019/7510315
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author Groh, Adrian
Jahn, Kirsten
Gröschl, Michael
Hillemacher, Thomas
Kornhuber, Johannes
Bleich, Stefan
Frieling, Helge
Heberlein, Annemarie
author_facet Groh, Adrian
Jahn, Kirsten
Gröschl, Michael
Hillemacher, Thomas
Kornhuber, Johannes
Bleich, Stefan
Frieling, Helge
Heberlein, Annemarie
author_sort Groh, Adrian
collection PubMed
description NGF and VEGF are known to be involved in different psychiatric diseases. In order to verify hints from basic research that both neurotrophines interact with each other, serum levels of NGF and VEGF were measured in a cohort of 33 healthy individuals and correlated. NGF level was 126.30 pg/mL (±155.43), and VEGF level was 57.28 pg/mL (±44.48). Both factors were significantly correlated, confirming their interaction and legitimising the usage of their respective ratio (0.8 (±0.42)) as a less varying additional marker in prospective studies.
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spelling pubmed-68852702019-12-11 Short Communication: Interaction of Nerve Growth Factor (NGF) and Vascular Endothelial Growth Factor (VEGF) in Healthy Individuals Groh, Adrian Jahn, Kirsten Gröschl, Michael Hillemacher, Thomas Kornhuber, Johannes Bleich, Stefan Frieling, Helge Heberlein, Annemarie Dis Markers Research Article NGF and VEGF are known to be involved in different psychiatric diseases. In order to verify hints from basic research that both neurotrophines interact with each other, serum levels of NGF and VEGF were measured in a cohort of 33 healthy individuals and correlated. NGF level was 126.30 pg/mL (±155.43), and VEGF level was 57.28 pg/mL (±44.48). Both factors were significantly correlated, confirming their interaction and legitimising the usage of their respective ratio (0.8 (±0.42)) as a less varying additional marker in prospective studies. Hindawi 2019-11-11 /pmc/articles/PMC6885270/ /pubmed/31827642 http://dx.doi.org/10.1155/2019/7510315 Text en Copyright © 2019 Adrian Groh et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Groh, Adrian
Jahn, Kirsten
Gröschl, Michael
Hillemacher, Thomas
Kornhuber, Johannes
Bleich, Stefan
Frieling, Helge
Heberlein, Annemarie
Short Communication: Interaction of Nerve Growth Factor (NGF) and Vascular Endothelial Growth Factor (VEGF) in Healthy Individuals
title Short Communication: Interaction of Nerve Growth Factor (NGF) and Vascular Endothelial Growth Factor (VEGF) in Healthy Individuals
title_full Short Communication: Interaction of Nerve Growth Factor (NGF) and Vascular Endothelial Growth Factor (VEGF) in Healthy Individuals
title_fullStr Short Communication: Interaction of Nerve Growth Factor (NGF) and Vascular Endothelial Growth Factor (VEGF) in Healthy Individuals
title_full_unstemmed Short Communication: Interaction of Nerve Growth Factor (NGF) and Vascular Endothelial Growth Factor (VEGF) in Healthy Individuals
title_short Short Communication: Interaction of Nerve Growth Factor (NGF) and Vascular Endothelial Growth Factor (VEGF) in Healthy Individuals
title_sort short communication: interaction of nerve growth factor (ngf) and vascular endothelial growth factor (vegf) in healthy individuals
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885270/
https://www.ncbi.nlm.nih.gov/pubmed/31827642
http://dx.doi.org/10.1155/2019/7510315
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