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The Effects of Clarithromycin on the Pharmacokinetics of Apixaban in Healthy Volunteers: A Single-Sequence Crossover Study

BACKGROUND: This was an open-label, phase I, nonrandomized, single-sequence, crossover study to evaluate the effect of concomitant administration of multiple doses of clarithromycin on the single-dose exposure, safety, and tolerability of apixaban in healthy subjects. METHODS: In total, 19 subjects...

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Detalles Bibliográficos
Autores principales:	Garonzik, Samira, Byon, Wonkyung, Myers, Elsa, Li, Xiodong, Marchisin, David, Murthy, Bindu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2019
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885504/ https://www.ncbi.nlm.nih.gov/pubmed/31030414 http://dx.doi.org/10.1007/s40256-019-00348-2

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