Cargando…

Aberrantly High Expression Of NOK/STYK1 Is Tightly Associated With The Activation Of The AKT/GSK3β/N-Cadherin Pathway In Non-Small Cell Lung Cancer

PURPOSE: High metastasis is a leading risk factor for the survival of non-small cell lung cancer (NSCLC) and epithelial-mesenchymal transition (EMT) is a vital step of metastasis. The expression of novel oncogene with kinase domain (NOK) has been observed in some human malignancies, including non-sm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Zhao, Ma, Nan, Xiong, Yan-Lu, Wang, Lei, Li, Wei-Miao, Lai, Yuan-Yang, Zhang, Chen-Xi, Zhang, Zhi-Pei, Li, Xiao-Fei, Zhao, Jin-Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885570/ https://www.ncbi.nlm.nih.gov/pubmed/31819514 http://dx.doi.org/10.2147/OTT.S210014

Ejemplares similares

Clinicopathologic features and prognostic implications of NOK/STYK1 protein expression in non-small cell lung cancer
por: Chen, Peng, et al.
Publicado: (2014)

STYK1/NOK Promotes Metastasis and Epithelial-Mesenchymal Transition in Non-small Cell Lung Cancer by Suppressing FoxO1 Signaling
por: Lai, Yuanyang, et al.
Publicado: (2021)

Downregulation of GLUT3 impairs STYK1/NOK-mediated metabolic reprogramming and proliferation in NIH-3T3 cells
por: Shi, Weiye, et al.
Publicado: (2021)

STYK1/NOK affects cell cycle late mitosis and directly interacts with anaphase-promoting complex activator CDH1
por: Zeng, Su-Lin, et al.
Publicado: (2022)

Aberrant expression of STYK1 and E-cadherin confer a poor prognosis for pancreatic cancer patients
por: Chen, Luguang, et al.
Publicado: (2017)

Aberrant STYK1 expression in ovarian cancer tissues and cell lines
por: Jackson, Kesmic A, et al.
Publicado: (2009)

Jorden går (nok) ikke under alligevel
Publicado: (2008)

Low STYK1 expression indicates poor prognosis in gastric cancer
por: Fang, Jian, et al.
Publicado: (2018)

Prevalence of Tinea Capitis among School Children in Nok Community of Kaduna State, Nigeria
por: Dogo, Josephine, et al.
Publicado: (2016)

RBM15 condensates modulate m(6)A modification of STYK1 to promote tumorigenesis
por: Jiang, Amin, et al.
Publicado: (2022)

Phosphorylated STYK1 restrains the inhibitory role of EGFR in autophagy initiation and EGFR-TKIs sensitivity
por: Zhou, Cefan, et al.
Publicado: (2022)

AB067. High novel oncogene with kinase-domain (NOK) gene expression is associated with the progression of renal cell carcinoma
por: Cao, Qingfei, et al.
Publicado: (2016)

Acute Ethanol Inhibition of γ Oscillations Is Mediated by Akt and GSK3β
por: Wang, JianGang, et al.
Publicado: (2016)

STYK1 promotes epithelial-mesenchymal transition and tumor metastasis in human hepatocellular carcinoma through MEK/ERK and PI3K/AKT signaling
por: Wang, Zhaowen, et al.
Publicado: (2016)

STYK1 promotes tumor growth and metastasis by reducing SPINT2/HAI-2 expression in non-small cell lung cancer
por: Ma, Zhiqiang, et al.
Publicado: (2019)

Knockdown of Serine Threonine Tyrosine Kinase 1 (STYK1) Inhibits the Migration and Tumorigenesis in Glioma Cells
por: Zhou, Jianping, et al.
Publicado: (2017)

Prostate‐specific antigen modulates the osteogenic differentiation of MSCs via the cadherin 11‐Akt axis
por: Wu, Longxiang, et al.
Publicado: (2020)

Daidzein ameliorated concanavalin A-induced liver injury through the Akt/GSK-3β/Nrf2 pathway in mice
por: Li, Shang-Lin, et al.
Publicado: (2021)

Lnc-STYK1-2 regulates bladder cancer cell proliferation, migration, and invasion by targeting miR-146b-5p expression and AKT/STAT3/NF-kB signaling
por: Dai, Ranran, et al.
Publicado: (2021)

Inhibition of mTORC1 induces loss of E-cadherin through AKT/GSK-3β signaling-mediated upregulation of E-cadherin repressor complexes in non-small cell lung cancer cells
por: Kim, Eun Young, et al.
Publicado: (2014)

MiR-650 represses high-risk non-metastatic colorectal cancer progression via inhibition of AKT2/GSK3β/E-cadherin pathway
por: Zhou, Chunxian, et al.
Publicado: (2017)

Girdin acts as an oncogene in gastric cancer by regulating AKT/GSK3β/β-catenin signaling
por: Wang, Yun, et al.
Publicado: (2023)

AKT/GSK3 signaling pathway and schizophrenia
por: Emamian, Effat S.
Publicado: (2012)

AKT/GSK3β Signaling in Glioblastoma
por: Majewska, Ewelina, et al.
Publicado: (2016)

Aberrant E-cadherin staining patterns in invasive mammary carcinoma
por: Harigopal, Malini, et al.
Publicado: (2005)

Targeting of cadherin-11 decreases skin fibrosis in the tight skin-1 mouse model
por: Pedroza, Mesias, et al.
Publicado: (2017)

Urocortin ameliorates diabetic cardiomyopathy in rats via the Akt/GSK-3β signaling pathway
por: LIU, XINYU, et al.
Publicado: (2015)

Cannabinoid receptors promote chronic intermittent hypoxia-induced breast cancer metastasis via IGF-1R/AKT/GSK-3β
por: Li, Li-Ting, et al.
Publicado: (2021)

CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK-3β/β-catenin pathway
por: Wang, Chuanzheng, et al.
Publicado: (2023)

Cadherin Cytoplasmic Domains Inhibit the Cell Surface Localization of Endogenous E-Cadherin, Blocking Desmosome and Tight Junction Formation and Inducing Cell Dissociation
por: Ozawa, Masayuki, et al.
Publicado: (2014)

OLA1 contributes to epithelial-mesenchymal transition in lung cancer by modulating the GSK3β/snail/E-cadherin signaling
por: Bai, Li, et al.
Publicado: (2016)

Expression analysis of E-cadherin, Slug and GSK3β in invasive ductal carcinoma of breast
por: Prasad, Chandra P, et al.
Publicado: (2009)

Aberrant P-cadherin expression is associated to aggressive feline mammary carcinomas
por: Figueira, Ana Catarina, et al.
Publicado: (2014)

Carnosic acid protects against pressure overload-induced cardiac remodelling by inhibiting the AKT/GSK3β/NOX4 signalling pathway
por: Wei, Yun-Jie, et al.
Publicado: (2020)

The EGFR-STYK1-FGF1 axis sustains functional drug tolerance to EGFR inhibitors in EGFR-mutant non-small cell lung cancer
por: Eggermont, Carolien, et al.
Publicado: (2022)

The potential dual effects of sevoflurane on AKT/GSK3β signaling pathway
por: Zhang, Lei, et al.
Publicado: (2014)

TMEM17 promotes malignant progression of breast cancer via AKT/GSK3β signaling
por: Zhao, Yue, et al.
Publicado: (2018)

Oridonin inhibits aberrant AKT activation in breast cancer
por: Sun, Bowen, et al.
Publicado: (2018)

Sanbai Melon Seed Oil Exerts Its Protective Effects in a Diabetes Mellitus Model via the Akt/GSK-3β/Nrf2 Pathway
por: Wang, Fang, et al.
Publicado: (2019)

E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning
por: Rübsam, Matthias, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_vonvt5j3mth08f29f3g1qj7udd