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Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma
Sarcoidosis is a systemic noncaseous granulomatous disease. The liver is a common location but usually asymptomatic. Current literature suggests an association between sarcoidosis and cancers. However, there is a lack of definite evidence. We present a case of a 59-year-old man with jaundice and acu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885758/ https://www.ncbi.nlm.nih.gov/pubmed/31827951 http://dx.doi.org/10.1155/2019/9383019 |
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author | Gupta, Kamesh Hassan, Tuyyab Rizwan, Shahid Hans, Bandhul Jawale, Rahul Desilets, David |
author_facet | Gupta, Kamesh Hassan, Tuyyab Rizwan, Shahid Hans, Bandhul Jawale, Rahul Desilets, David |
author_sort | Gupta, Kamesh |
collection | PubMed |
description | Sarcoidosis is a systemic noncaseous granulomatous disease. The liver is a common location but usually asymptomatic. Current literature suggests an association between sarcoidosis and cancers. However, there is a lack of definite evidence. We present a case of a 59-year-old man with jaundice and acutely elevated alkaline phosphatase. The diagnosis was confirmed by obtaining a liver biopsy and was treated with 6 months of steroids. A year later, he had a recurrence of jaundice. MRCP showed biliary dilatation and a mass in the pancreatic head, confirmed by biopsy to be adenocarcinoma. This is the first case to be reported of hepatic sarcoidosis associated with pancreatic cancer. |
format | Online Article Text |
id | pubmed-6885758 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-68857582019-12-11 Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma Gupta, Kamesh Hassan, Tuyyab Rizwan, Shahid Hans, Bandhul Jawale, Rahul Desilets, David Case Reports Hepatol Case Report Sarcoidosis is a systemic noncaseous granulomatous disease. The liver is a common location but usually asymptomatic. Current literature suggests an association between sarcoidosis and cancers. However, there is a lack of definite evidence. We present a case of a 59-year-old man with jaundice and acutely elevated alkaline phosphatase. The diagnosis was confirmed by obtaining a liver biopsy and was treated with 6 months of steroids. A year later, he had a recurrence of jaundice. MRCP showed biliary dilatation and a mass in the pancreatic head, confirmed by biopsy to be adenocarcinoma. This is the first case to be reported of hepatic sarcoidosis associated with pancreatic cancer. Hindawi 2019-11-19 /pmc/articles/PMC6885758/ /pubmed/31827951 http://dx.doi.org/10.1155/2019/9383019 Text en Copyright © 2019 Kamesh Gupta et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Gupta, Kamesh Hassan, Tuyyab Rizwan, Shahid Hans, Bandhul Jawale, Rahul Desilets, David Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma |
title | Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma |
title_full | Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma |
title_fullStr | Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma |
title_full_unstemmed | Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma |
title_short | Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma |
title_sort | hepatic sarcoidosis complicated with pancreatic adenocarcinoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885758/ https://www.ncbi.nlm.nih.gov/pubmed/31827951 http://dx.doi.org/10.1155/2019/9383019 |
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