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Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma

Sarcoidosis is a systemic noncaseous granulomatous disease. The liver is a common location but usually asymptomatic. Current literature suggests an association between sarcoidosis and cancers. However, there is a lack of definite evidence. We present a case of a 59-year-old man with jaundice and acu...

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Autores principales: Gupta, Kamesh, Hassan, Tuyyab, Rizwan, Shahid, Hans, Bandhul, Jawale, Rahul, Desilets, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885758/
https://www.ncbi.nlm.nih.gov/pubmed/31827951
http://dx.doi.org/10.1155/2019/9383019
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author Gupta, Kamesh
Hassan, Tuyyab
Rizwan, Shahid
Hans, Bandhul
Jawale, Rahul
Desilets, David
author_facet Gupta, Kamesh
Hassan, Tuyyab
Rizwan, Shahid
Hans, Bandhul
Jawale, Rahul
Desilets, David
author_sort Gupta, Kamesh
collection PubMed
description Sarcoidosis is a systemic noncaseous granulomatous disease. The liver is a common location but usually asymptomatic. Current literature suggests an association between sarcoidosis and cancers. However, there is a lack of definite evidence. We present a case of a 59-year-old man with jaundice and acutely elevated alkaline phosphatase. The diagnosis was confirmed by obtaining a liver biopsy and was treated with 6 months of steroids. A year later, he had a recurrence of jaundice. MRCP showed biliary dilatation and a mass in the pancreatic head, confirmed by biopsy to be adenocarcinoma. This is the first case to be reported of hepatic sarcoidosis associated with pancreatic cancer.
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spelling pubmed-68857582019-12-11 Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma Gupta, Kamesh Hassan, Tuyyab Rizwan, Shahid Hans, Bandhul Jawale, Rahul Desilets, David Case Reports Hepatol Case Report Sarcoidosis is a systemic noncaseous granulomatous disease. The liver is a common location but usually asymptomatic. Current literature suggests an association between sarcoidosis and cancers. However, there is a lack of definite evidence. We present a case of a 59-year-old man with jaundice and acutely elevated alkaline phosphatase. The diagnosis was confirmed by obtaining a liver biopsy and was treated with 6 months of steroids. A year later, he had a recurrence of jaundice. MRCP showed biliary dilatation and a mass in the pancreatic head, confirmed by biopsy to be adenocarcinoma. This is the first case to be reported of hepatic sarcoidosis associated with pancreatic cancer. Hindawi 2019-11-19 /pmc/articles/PMC6885758/ /pubmed/31827951 http://dx.doi.org/10.1155/2019/9383019 Text en Copyright © 2019 Kamesh Gupta et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gupta, Kamesh
Hassan, Tuyyab
Rizwan, Shahid
Hans, Bandhul
Jawale, Rahul
Desilets, David
Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma
title Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma
title_full Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma
title_fullStr Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma
title_full_unstemmed Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma
title_short Hepatic Sarcoidosis Complicated with Pancreatic Adenocarcinoma
title_sort hepatic sarcoidosis complicated with pancreatic adenocarcinoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885758/
https://www.ncbi.nlm.nih.gov/pubmed/31827951
http://dx.doi.org/10.1155/2019/9383019
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