Cabazitaxel Induced Thrombotic Microangiopathy in a Patient with Prostate Cancer

Cancer-associated thrombotic microangiopathy (TMA) refers to a group of disorders characterized by microangiopathic haemolytic anemia, thrombocytopenia, and ischemic organ damage. TMA manifestations can be induced by cancer or by chemotherapy. We report the case of a 64-year-old man with metastatic...

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Detalles Bibliográficos
Autores principales: Nlandu, Yannick, Pourcine, Franck, Vong, Ly van phach, Chelly, Jonathan, Jochmans, Sebastien, Mazerand, Sandie, Monchi, Mehran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885798/
https://www.ncbi.nlm.nih.gov/pubmed/31827954
http://dx.doi.org/10.1155/2019/8591283
Descripción
Sumario:Cancer-associated thrombotic microangiopathy (TMA) refers to a group of disorders characterized by microangiopathic haemolytic anemia, thrombocytopenia, and ischemic organ damage. TMA manifestations can be induced by cancer or by chemotherapy. We report the case of a 64-year-old man with metastatic prostate cancer who experienced a Cabazitaxel-induced TMA manifestation. TMA responds to conservative therapy, dialysis without plasmaphoresis, with progressive recovered renal function.

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