Cabazitaxel Induced Thrombotic Microangiopathy in a Patient with Prostate Cancer

Cancer-associated thrombotic microangiopathy (TMA) refers to a group of disorders characterized by microangiopathic haemolytic anemia, thrombocytopenia, and ischemic organ damage. TMA manifestations can be induced by cancer or by chemotherapy. We report the case of a 64-year-old man with metastatic...

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Autores principales: Nlandu, Yannick, Pourcine, Franck, Vong, Ly van phach, Chelly, Jonathan, Jochmans, Sebastien, Mazerand, Sandie, Monchi, Mehran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885798/
https://www.ncbi.nlm.nih.gov/pubmed/31827954
http://dx.doi.org/10.1155/2019/8591283
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author Nlandu, Yannick
Pourcine, Franck
Vong, Ly van phach
Chelly, Jonathan
Jochmans, Sebastien
Mazerand, Sandie
Monchi, Mehran
author_facet Nlandu, Yannick
Pourcine, Franck
Vong, Ly van phach
Chelly, Jonathan
Jochmans, Sebastien
Mazerand, Sandie
Monchi, Mehran
author_sort Nlandu, Yannick
collection PubMed
description Cancer-associated thrombotic microangiopathy (TMA) refers to a group of disorders characterized by microangiopathic haemolytic anemia, thrombocytopenia, and ischemic organ damage. TMA manifestations can be induced by cancer or by chemotherapy. We report the case of a 64-year-old man with metastatic prostate cancer who experienced a Cabazitaxel-induced TMA manifestation. TMA responds to conservative therapy, dialysis without plasmaphoresis, with progressive recovered renal function.
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spelling pubmed-68857982019-12-11 Cabazitaxel Induced Thrombotic Microangiopathy in a Patient with Prostate Cancer Nlandu, Yannick Pourcine, Franck Vong, Ly van phach Chelly, Jonathan Jochmans, Sebastien Mazerand, Sandie Monchi, Mehran Case Rep Nephrol Case Report Cancer-associated thrombotic microangiopathy (TMA) refers to a group of disorders characterized by microangiopathic haemolytic anemia, thrombocytopenia, and ischemic organ damage. TMA manifestations can be induced by cancer or by chemotherapy. We report the case of a 64-year-old man with metastatic prostate cancer who experienced a Cabazitaxel-induced TMA manifestation. TMA responds to conservative therapy, dialysis without plasmaphoresis, with progressive recovered renal function. Hindawi 2019-11-19 /pmc/articles/PMC6885798/ /pubmed/31827954 http://dx.doi.org/10.1155/2019/8591283 Text en Copyright © 2019 Yannick Nlandu et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Nlandu, Yannick
Pourcine, Franck
Vong, Ly van phach
Chelly, Jonathan
Jochmans, Sebastien
Mazerand, Sandie
Monchi, Mehran
Cabazitaxel Induced Thrombotic Microangiopathy in a Patient with Prostate Cancer
title Cabazitaxel Induced Thrombotic Microangiopathy in a Patient with Prostate Cancer
title_full Cabazitaxel Induced Thrombotic Microangiopathy in a Patient with Prostate Cancer
title_fullStr Cabazitaxel Induced Thrombotic Microangiopathy in a Patient with Prostate Cancer
title_full_unstemmed Cabazitaxel Induced Thrombotic Microangiopathy in a Patient with Prostate Cancer
title_short Cabazitaxel Induced Thrombotic Microangiopathy in a Patient with Prostate Cancer
title_sort cabazitaxel induced thrombotic microangiopathy in a patient with prostate cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885798/
https://www.ncbi.nlm.nih.gov/pubmed/31827954
http://dx.doi.org/10.1155/2019/8591283
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