Testosterone Replacement Therapy and the Risk of Hypoglycemia

We report the case of a 45-year-old man with a history of Klinefelter syndrome undergoing testosterone replacement therapy, and with type 2 diabetes treated with metformin with poor metabolic control. When vildagliptin was added to his treatment, he presented hypoglycemia after the testosterone inje...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Analía Verónica, Costanzo, Pablo René, Peuchot, Verónica Andrea, Knoblovits, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885825/
https://www.ncbi.nlm.nih.gov/pubmed/31827946
http://dx.doi.org/10.1155/2019/9616125
Descripción
Sumario:We report the case of a 45-year-old man with a history of Klinefelter syndrome undergoing testosterone replacement therapy, and with type 2 diabetes treated with metformin with poor metabolic control. When vildagliptin was added to his treatment, he presented hypoglycemia after the testosterone injection. We highlight this not widely reported drug interaction between hypoglycemic agents and testosterone.

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