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Massive computational identification of somatic variants in exonic splicing enhancers using The Cancer Genome Atlas

Owing to the development of next‐generation sequencing (NGS) technologies, a large number of somatic variants have been identified in various types of cancer. However, the functional significance of most somatic variants remains unknown. Somatic variants that occur in exonic splicing enhancer (ESE)...

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Detalles Bibliográficos
Autores principales: Tanimoto, Kousuke, Muramatsu, Tomoki, Inazawa, Johji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6885893/
https://www.ncbi.nlm.nih.gov/pubmed/31631560
http://dx.doi.org/10.1002/cam4.2619