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Statistical modeling of STR capillary electrophoresis signal

BACKGROUND: In order to isolate an individual’s genotype from a sample of biological material, most laboratories use PCR and Capillary Electrophoresis (CE) to construct a genetic profile based on polymorphic loci known as Short Tandem Repeats (STRs). The resulting profile consists of CE signal which...

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Detalles Bibliográficos
Autores principales: Karkar, Slim, Alfonse, Lauren E., Grgicak, Catherine M., Lun, Desmond S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886162/
https://www.ncbi.nlm.nih.gov/pubmed/31787097
http://dx.doi.org/10.1186/s12859-019-3074-0