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Fibroblast-like synovial cell production of extra domain A fibronectin associates with inflammation in osteoarthritis

BACKGROUND: The pathophysiology of osteoarthritis (OA) involves wear and tear, and a state of low-grade inflammation. Tissue repair responses include transforming growth factor beta (TGFβ)-induced myofibroblast production of extracellular matrix. Fibronectins are an essential part of the extracellul...

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Detalles Bibliográficos
Autores principales: Kragstrup, Tue W., Sohn, Dong H., Lepus, Christin M., Onuma, Kazuhiro, Wang, Qian, Robinson, William H., Sokolove, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886182/
https://www.ncbi.nlm.nih.gov/pubmed/31819923
http://dx.doi.org/10.1186/s41927-019-0093-4