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Optic Disc and Cup Segmentation in Retinal Images for Glaucoma Diagnosis by Locally Statistical Active Contour Model with Structure Prior

Accurate optic disc and optic cup segmentation plays an important role for diagnosing glaucoma. However, most existing segmentation approaches suffer from the following limitations. On the one hand, image devices or illumination variations always lead to intensity inhomogeneity in the fundus image....

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Yi, Yugen, Gao, Yuan, Dai, Jiangyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886352/
https://www.ncbi.nlm.nih.gov/pubmed/31827591
http://dx.doi.org/10.1155/2019/8973287
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author Zhou, Wei
Yi, Yugen
Gao, Yuan
Dai, Jiangyan
author_facet Zhou, Wei
Yi, Yugen
Gao, Yuan
Dai, Jiangyan
author_sort Zhou, Wei
collection PubMed
description Accurate optic disc and optic cup segmentation plays an important role for diagnosing glaucoma. However, most existing segmentation approaches suffer from the following limitations. On the one hand, image devices or illumination variations always lead to intensity inhomogeneity in the fundus image. On the other hand, the spatial prior knowledge of optic disc and optic cup, e.g., the optic cup is always contained inside the optic disc region, is ignored. Therefore, the effectiveness of segmentation approaches is greatly reduced. Different from most previous approaches, we present a novel locally statistical active contour model with the structure prior (LSACM-SP) approach to jointly and robustly segment the optic disc and optic cup structures. First, some preprocessing techniques are used to automatically extract initial contour of object. Then, we introduce the locally statistical active contour model (LSACM) to optic disc and optic cup segmentation in the presence of intensity inhomogeneity. Finally, taking the specific morphology of optic disc and optic cup into consideration, a novel structure prior is proposed to guide the model to generate accurate segmentation results. Experimental results demonstrate the advantage and superiority of our approach on two publicly available databases, i.e., DRISHTI-GS and RIM-ONE r2, by comparing with some well-known algorithms.
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spelling pubmed-68863522019-12-11 Optic Disc and Cup Segmentation in Retinal Images for Glaucoma Diagnosis by Locally Statistical Active Contour Model with Structure Prior Zhou, Wei Yi, Yugen Gao, Yuan Dai, Jiangyan Comput Math Methods Med Research Article Accurate optic disc and optic cup segmentation plays an important role for diagnosing glaucoma. However, most existing segmentation approaches suffer from the following limitations. On the one hand, image devices or illumination variations always lead to intensity inhomogeneity in the fundus image. On the other hand, the spatial prior knowledge of optic disc and optic cup, e.g., the optic cup is always contained inside the optic disc region, is ignored. Therefore, the effectiveness of segmentation approaches is greatly reduced. Different from most previous approaches, we present a novel locally statistical active contour model with the structure prior (LSACM-SP) approach to jointly and robustly segment the optic disc and optic cup structures. First, some preprocessing techniques are used to automatically extract initial contour of object. Then, we introduce the locally statistical active contour model (LSACM) to optic disc and optic cup segmentation in the presence of intensity inhomogeneity. Finally, taking the specific morphology of optic disc and optic cup into consideration, a novel structure prior is proposed to guide the model to generate accurate segmentation results. Experimental results demonstrate the advantage and superiority of our approach on two publicly available databases, i.e., DRISHTI-GS and RIM-ONE r2, by comparing with some well-known algorithms. Hindawi 2019-11-20 /pmc/articles/PMC6886352/ /pubmed/31827591 http://dx.doi.org/10.1155/2019/8973287 Text en Copyright © 2019 Wei Zhou et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhou, Wei
Yi, Yugen
Gao, Yuan
Dai, Jiangyan
Optic Disc and Cup Segmentation in Retinal Images for Glaucoma Diagnosis by Locally Statistical Active Contour Model with Structure Prior
title Optic Disc and Cup Segmentation in Retinal Images for Glaucoma Diagnosis by Locally Statistical Active Contour Model with Structure Prior
title_full Optic Disc and Cup Segmentation in Retinal Images for Glaucoma Diagnosis by Locally Statistical Active Contour Model with Structure Prior
title_fullStr Optic Disc and Cup Segmentation in Retinal Images for Glaucoma Diagnosis by Locally Statistical Active Contour Model with Structure Prior
title_full_unstemmed Optic Disc and Cup Segmentation in Retinal Images for Glaucoma Diagnosis by Locally Statistical Active Contour Model with Structure Prior
title_short Optic Disc and Cup Segmentation in Retinal Images for Glaucoma Diagnosis by Locally Statistical Active Contour Model with Structure Prior
title_sort optic disc and cup segmentation in retinal images for glaucoma diagnosis by locally statistical active contour model with structure prior
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886352/
https://www.ncbi.nlm.nih.gov/pubmed/31827591
http://dx.doi.org/10.1155/2019/8973287
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