Anti-apoptotic BCL2L2 increases megakaryocyte proplatelet formation in cultures of human cord blood

Apoptosis is a recognized limitation to generating large numbers of megakaryocytes in culture. The genes responsible have been rigorously studied in vivo in mice, but are poorly characterized in human culture systems. As CD34-positive ((+)) cells isolated from human umbilical vein cord blood were di...

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Detalles Bibliográficos
Autores principales: Bhatlekar, Seema, Basak, Indranil, Edelstein, Leonard C., Campbell, Robert A., Lindsey, Cory R., Italiano, Joseph E., Weyrich, Andrew S., Rowley, Jesse W., Rondina, Matthew T., Sola-Visner, Martha, Bray, Paul F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886406/
https://www.ncbi.nlm.nih.gov/pubmed/30733267
http://dx.doi.org/10.3324/haematol.2018.204685

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