Identifying gene function and module connections by the integration of multispecies expression compendia

The functions of many eukaryotic genes are still poorly understood. Here, we developed and validated a new method, termed GeneBridge, which is based on two linked approaches to impute gene function and bridge genes with biological processes. First, Gene-Module Association Determination (G-MAD) allow...

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Detalles Bibliográficos
Autores principales: Li, Hao, Rukina, Daria, David, Fabrice P.A., Li, Terytty Yang, Oh, Chang-Myung, Gao, Arwen W., Katsyuba, Elena, Bou Sleiman, Maroun, Komljenovic, Andrea, Huang, Qingyao, Williams, Robert W., Robinson-Rechavi, Marc, Schoonjans, Kristina, Morgenthaler, Stephan, Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886503/
https://www.ncbi.nlm.nih.gov/pubmed/31754022
http://dx.doi.org/10.1101/gr.251983.119

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