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Activation of ATM-c-IAP1 Pathway Mediates the Protective Effects of Estradiol in Human Vascular Endothelial Cells Exposed to Intermittent Hypoxia

PURPOSE: Chronic intermittent hypoxia (CIH) contributes to the increased risk of cardiovascular diseases in obstructive sleep apnea (OSA). We previously reported the anti-apoptotic effects of estradiol (E2) on IH-exposed human umbilical vein endothelial cells (HUVECs). Herein, we employed a proteomi...

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Detalles Bibliográficos
Autores principales:	Lin, Ying Ni, Lan, Xiao Fei, Liu, Zhuo Ran, Yan, Ya Ru, Zhou, Jian Ping, Li, Ning, Sun, Xian Wen, Li, Qing Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886551/ https://www.ncbi.nlm.nih.gov/pubmed/31819689 http://dx.doi.org/10.2147/NSS.S231456

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