Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products

Interleukin (IL)-17 signaling to the intestinal epithelium regulates the intestinal microbiome. Given the reported links between intestinal dysbiosis, bacterial translocation, and liver disease, we hypothesize that intestinal IL-17R signaling plays a critical role in mitigating hepatic inflammation....

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Detalles Bibliográficos
Autores principales: Cruz, Patricia Castillo-dela, Wanek, Alanna G., Kumar, Pawan, An, Xiaojing, Elsegeiny, Waleed, Horne, William, Fitch, Adam, Burr, Ansen H.P., Gopalakrishna, Kathyayini P., Chen, Kong, Methé, Barbara A., Canna, Scott W., Hand, Timothy W., Kolls, Jay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886715/
https://www.ncbi.nlm.nih.gov/pubmed/31747600
http://dx.doi.org/10.1016/j.celrep.2019.10.042

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