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High-throughput genotyping of a full voltage-gated sodium channel gene via genomic DNA using target capture sequencing and analytical pipeline MoNaS to discover novel insecticide resistance mutations

In insects, the voltage-gated sodium channel (VGSC) is the primary target site of pyrethroid insecticides. Various amino acid substitutions in the VGSC protein, which are selected under insecticide pressure, are known to confer insecticide resistance. In the genome, the VGSC gene consists of more th...

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Detalles Bibliográficos
Autores principales: Itokawa, Kentaro, Sekizuka, Tsuyoshi, Maekawa, Yoshihide, Yatsu, Koji, Komagata, Osamu, Sugiura, Masaaki, Sasaki, Tomonori, Tomita, Takashi, Kuroda, Makoto, Sawabe, Kyoko, Kasai, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886866/
https://www.ncbi.nlm.nih.gov/pubmed/31738756
http://dx.doi.org/10.1371/journal.pntd.0007818

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