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Kinetics of HTLV-1 reactivation from latency quantified by single-molecule RNA FISH and stochastic modelling

The human T cell leukemia virus HTLV-1 establishes a persistent infection in vivo in which the viral sense-strand transcription is usually silent at a given time in each cell. However, cellular stress responses trigger the reactivation of HTLV-1, enabling the virus to transmit to a new host cell. Us...

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Detalles Bibliográficos
Autores principales: Miura, Michi, Dey, Supravat, Ramanayake, Saumya, Singh, Abhyudai, Rueda, David S., Bangham, Charles R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6886867/
https://www.ncbi.nlm.nih.gov/pubmed/31738810
http://dx.doi.org/10.1371/journal.ppat.1008164